대한세포병리학회지 (The Korean Journal of Cytopathology)

대한세포병리학회 (The Korean Society for Cytopathology)
권호 표지

경추에 발생한 척삭종의 세침흡인 세포학적 소견 - 1예 보고 -

Fine Needle Aspiration Cytology of Cervical Chordoma - A Case Report -

  • 양경무 (연세대학교 원주의과대학 병리학교실) ;
  • 조미연 (연세대학교 원주의과대학 병리학교실) ;
  • 정순희 (연세대학교 원주의과대학 병리학교실) ;
  • 봉정표 (연세대학교 원주의과대학 이비인후과학교실)
  • Yang, Kyung-Moo (Department of Pathology Yonsei University, Wonju College of Medicine) ;
  • Cho, Mee-Yon (Department of Pathology Yonsei University, Wonju College of Medicine) ;
  • Jung, Soon-Hee (Department of Pathology Yonsei University, Wonju College of Medicine) ;
  • Bong, Jeong-Pyo (Department of Head and Neck Surgery, Yonsei University, Wonju College of Medicine)
  • 발행 : 1997.06.30
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초록

A case of cervical chordoma diagnosed by fine needle aspiration is discussed. A 41year-old male was admitted due to dyspnea on neck flexion. Radiologic image revealed a retrotracheal superior mediastinal solid mass. Aspiration cytology showed many clusters of oval or large polygonal cells having abundant eosinophilic or bubbly cytoplasm in an amorphous blue-gray mucoid background. The nuclei were round and showed size variation, coarse granular chromatin, and indistinct nucleoli. Some cells contained brown granular pigments in the cytoplasm. Mitoses were rarely found. The cytoplasm was strongly positive for PAS stain. Immunohistochemical stains using cell block revealed positive reaction for cytokerain, EMA, vimentin, and S-100 protein. The confirmative diagnosis was made by following excisional biopsy. Electron microscopic study revealed large pools of intracytoplasmic glycogen and microfilaments. This is the first case of cervical chordoma diagnosed by aspiration cytology to our knowledge in Korean literature.

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