Journal of Preventive Medicine and Public Health
- 제30권3호
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- Pages.585-598
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- 1997
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- 1975-8375(pISSN)
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- 2233-4521(eISSN)
대기오염에 의한 폐암 및 만성폐색성호흡기질환 -개인 흡연력을 보정한 만성건강영향평가-
Lung cancer, chronic obstructive pulmonary disease and air pollution
- 성주헌 (서울대학교 의과대학 예방의학교실) ;
- 조수헌 (서울대학교 의과대학 예방의학교실) ;
- 강대희 (서울대학교 의과대학 예방의학교실) ;
- 유근영 (서울대학교 의과대학 예방의학교실)
- Sung, Joo-Hon (Department of Preventive Medicine, Seoul National University College of Medicine) ;
- Cho, Soo-Hun (Department of Preventive Medicine, Seoul National University College of Medicine) ;
- Kang, Dae-Hee (Department of Preventive Medicine, Seoul National University College of Medicine) ;
- Yoo, Keun-Young (Department of Preventive Medicine, Seoul National University College of Medicine)
- 발행 : 1997.09.01
초록
Background : Although there are growing concerns about the adverse health effect of air pollution, not much evidence on health effect of current air pollution level had been accumulated yet in Korea. This study was designed to evaluate the chronic health effect of ai. pollution using Korean Medical Insurance Corporation (KMIC) data and air quality data. Medical insurance data in Korea have some drawback in accuracy, but they do have some strength especially in their national coverage, in having unified ID system and individual information which enables various data linkage and chronic health effect study. Method : This study utilized the data of Korean Environmental Surveillance System Study (Surveillance Study), which consist of asthma, acute bronchitis, chronic obstructive pulmonary diseases (COPD), cardiovascular diseases (congestive heart failure and ischemic heart disease), all cancers, accidents and congenital anomaly, i. e., mainly potential environmental diseases. We reconstructed a nested case-control study wit5h Surveillance Study data and air pollution data in Korea. Among 1,037,210 insured who completed? questionnaire and physical examination in 1992, disease free (for chronic respiratory disease and cancer) persons, between the age of 35-64 with smoking status information were selected to reconstruct cohort of 564,991 persons. The cohort was followed-up to 1995 (1992-5) and the subjects who had the diseases in Surveillance Study were selected. Finally, the patients, with address information and available air pollution data, left to be 'final subjects' Cases were defined to all lung cancer cases (424) and COPD admission cases (89), while control groups are determined to all other patients than two case groups among 'final subjects'. That is, cases are putative chronic environmental diseases, while controls are mainly acute environmental diseases. for exposure, Air quality data in 73 monitoring sites between 1991 - 1993 were analyzed to surrogate air pollution exposure level of located areas (58 areas). Five major air pollutants data, TSP,