Journal of Periodontal and Implant Science
- 제27권4호
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- Pages.883-908
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- 1997
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
치주조직 유관세포에서의 Nitric Oxide 및 Nitric Oxide Synthetase의 생물학적 특성에 관한 연구
An Experimental Study on the Biological Specificity of Nitric Oxide and Nitric Oxide Synthetase in Periodontium-Related Cells
- 윤형진 (원광대학교 치과대학 치주과학교실) ;
- 윤동환 (원광대학교 치과대학 치주과학교실) ;
-
유형근
(원광대학교 치과대학 치주과학교실) ;
-
신형식
(원광대학교 치과대학 치주과학교실)
- Yoon, Hyung-Jin (Dept. of Periodontology, College of Dentistry, Wonkwang University) ;
- Yoon, Dong-Whan (Dept. of Periodontology, College of Dentistry, Wonkwang University) ;
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You, Hyung-Keun
(Dept. of Periodontology, College of Dentistry, Wonkwang University) ;
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Shin, Hyung-Shik
(Dept. of Periodontology, College of Dentistry, Wonkwang University)
- 발행 : 1997.12.31
초록
Bone remodeling is characterized by the coupling of osteoclast-mediated bone resorption and osteoblast-mediated bone formation. The process is tightly regualted at the local level by an incompletely known netwotk of peptide and non-peptide fators. Nitric oxide(NO), synthesized by nitric oxide synthetase(NOS) from L-arginine, is becoming recognized as an important bioregualtory molecule in a variety of tissue, but little is known about its possible role in periodontal tissue. The purpose of this study is to investigate the expression of nitric oxide synthetase(NOS) in inflamed gingiva and the effects of cytokine on the expression of NOS protein. The expression of NOS in gingival tissue was evaluated by immunohistochemical staining for
키워드