Journal of Periodontal and Implant Science
- Volume 27 Issue 4
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- Pages.785-804
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- 1997
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
The effects of a combination of calcium sulfate and platelet-derived growth factor on periodontal ligament cells in vitro
Calcium sulfate와 혈소판 유래성장인자의 혼합사용이 치주인대세포에 미치는 영향
- Kim, Jun-Seong (Department of Periodontology, College of Dentistry, Yonsei University, Research Institute for Periodontal Regeneration) ;
- Choi, Seong-Ho (Department of Periodontology, College of Dentistry, Yonsei University, Research Institute for Periodontal Regeneration) ;
- Yu, Yun-Jung (Department of Oral Biology, College of Dentistry, Yonsei University) ;
- Chai, Jung-Kiu (Department of Periodontology, College of Dentistry, Yonsei University, Research Institute for Periodontal Regeneration) ;
- Kim, Chong-Kwan (Department of Periodontology, College of Dentistry, Yonsei University, Research Institute for Periodontal Regeneration) ;
- Cho, Kyoo-Sung (Department of Periodontology, College of Dentistry, Yonsei University, Research Institute for Periodontal Regeneration)
- 김준성 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
- 최성호 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
- 유윤정 (연세대학교 치과대학 구강생물학교실) ;
- 채중규 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
- 김종관 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
- 조규성 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소)
- Published : 1997.12.31
Abstract
It was well known that calcium sulfate was biocompatible, resorbed rapidly in the body, had potential as a good barrier membrane. Platelet-derived growth factor(PDGF) was one of polypeptide growth factor that had been reported as a biological mediator which regulates activities of wound healing process including the cell proliferation, migration and metabolism. The purpose of this study was to evaluate the effects of a combination of calcium sulfate and PDGF on periodontal ligament cells in vitro to use as a regeneration promoting agent of periodontal tissue. Human periodontal ligament cells were prepared from the premolar tooth extracted for the orthodontic treatment. Cells were cultured in
Keywords
- calcium sulfate;
- platelet-derived growth factor(PDGF) biocompatible;
- vehicle;
- periodontal tissue regeneration