Journal of Periodontal and Implant Science
- Volume 27 Issue 4
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- Pages.669-684
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- 1997
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
The Effect of IGF-1 on ALP Activity of MC3T3-E1 Cell
MC3T3-E1세포의 ALP activity에 대한 IGF-I의 영향
- Lee, Hu-Jung (Department of Periodontology, School of Dentistry, Kyungpook National University) ;
- Lee, Jae-Mok (Department of Periodontology, School of Dentistry, Kyungpook National University) ;
- Choi, Byung-Ju (Department of Dental Pharmacology, School of Dentistry, Kyungpook National University) ;
- Yu, Hyun-Mo (Department of Oral Biochemistry, School of Dentistry, Kyungpook National University) ;
- Shu, Jo-Young (Department of Periodontology, School of Dentistry, Kyungpook National University)
- 이후정 (경북대학교 치과대학 치주과학교실) ;
- 이재목 (경북대학교 치과대학 치주과학교실) ;
- 최병주 (경북대학교 치과대학 치과약리학교실) ;
- 유현모 (경북대학교 치과대학 구강생화학교실) ;
- 서조영 (경북대학교 치과대학 치주과학교실)
- Published : 1997.12.31
Abstract
Polypeptide growth factors belong to a class of potent biologic mediators which regulate cell differentiation, proliferation, migration and metabolism. IGF-I is polypeptides secreted by skeletal cells and is considered as regulators of bone formation. The purpose of this study is to evaluate the effects of IGF-I on bone nodule formation and alkaline phosphatase activity of MC3T3-E1 cells. MC3T3-E1 cells were seeded at
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