우리나라 일부지역 119구조구급대원의 HBsAg 및 Anti-HBs 검출에 있어서 EIA법과 RPHA법 및 PHA법에 따른 양성률비교

Comparison Study of Positive Rates According to the Methods of EIA, RHA and PHA in Detecting of HBsAg, Anti-HBs Among -119 Emergency Medical Technicians and Rescuers in Korea

This study of the positive rates of HBsAg, anti-HBs among 119 Emergency Medical Technicians and Rescuers who were working in Pohang, Kyoung-Buk, Korea was performed from March to June 1997 according to three methods of EIA, RPHA and PHA. The number of samples were 201. The results were as follows; The overall positive rate of HBs Ag by EIA and RPHA methods were 4.98%, 5.47%, the overall positive rate of anti-HBs by EIA and PHA methods were 58.71%, 63.68%. In detecting of HBs Ag, concurrence rate, sensitivity, specificity and predictability of PHA to EIA were 99.5%, 90.9%, 100% and 99.75% respectively. In detecting of anti-HBs, concurrence rate, sensitivity, specificity and predictability of PHA to EIA were 91.04%, 89%, 94.5% and 89.87% respectively. Based on this study, there were no significant diffrences in the positive rates of HBsAg and Anti-HBs in 119 Emergency Medical Technicians and Rescurers in Pohang, Korea as compared with the general population according to other studies. In terms of concurrence rate, sensitivity, specificity and the costs of RPHA with EIA for detecting HBsAg, RPHA is more cost effective than EIA for mass screening of HBsAg detection. Also, In terms of concurrence rate, sensitivity and specificity of PHA with EIA, PHA is more cost effective and less problems of procedure than the EIA for mass screening of Anti-HBs detection.