Journal of Microbiology and Biotechnology
- Volume 7 Issue 6
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- Pages.429-434
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- 1997
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- 1017-7825(pISSN)
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- 1738-8872(eISSN)
Neuronal Cell Protection Activity of Macrolactin A Produced by Actinomadura sp.
- Kim, Hyeon-Ho (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
- Kim, Won-Gon (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
- Ryoo, In-Ja (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
- Kim, Chang-Jin (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
- Suk, Jae-Eun (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
- Han, Kyou-Hoon (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
- Hwang, Se-Young (Graduate School of Biotechnology, Korea University) ;
- Yoo, Ick-Dong (Korea Research Institute of Bioscience and Biotechnology, KIST)
- Published : 1997.12.01
Abstract
Macrolactin A, 24-membered macrolide, was isolated from the culture broth of Actinomadura sp. as a neuronal cell protecting substance. In the cell assay, this compound inhibited glutamate toxicity in N18-RE-105 cells with an