Journal of Microbiology and Biotechnology
- Volume 7 Issue 4
- /
- Pages.262-266
- /
- 1997
- /
- 1017-7825(pISSN)
- /
- 1738-8872(eISSN)
Production of 1-Deoxynojirimycin by Streptomyces sp. SID9135
- Paek, Nam-Soo (Il Dong Pharmaceutical Co., Research Laboratories) ;
- Kang, Dae-Jung (Il Dong Pharmaceutical Co., Research Laboratories) ;
- Choi, Yong-Jin (Graduate School of Biotechnology, Korea University) ;
- Lee, Jung-Jun (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
- Kim, Tae-Han (Il Dong Pharmaceutical Co., Research Laboratories) ;
- Kim, Kee-Won (Il Dong Pharmaceutical Co., Research Laboratories)
- Published : 1997.08.01
Abstract
To increase the high production of 1-deoxynojirimycin (DNJ) from Streptomyces sp. SID9135, the effect of various carbon sources, nitrogen sources, cationic metal ions, the initial pH of the medium, and agitation speed were investigated. The most effective carbon and nitrogen sources were found to be lactose 2.5% (w/v) and soybean meal 2.0% (w/v), respectively. None of the cationic metal ions examined had any detectable stimulating effect on DNJ production except