Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
권호 표지

Correlation Among Permeability, Apparent Density, And Porosity of Human Lumbar Vertebral Trabecular Bone

인체 요추해면골의 배류계수, 겉보기밀도, 공극비 사이의 상관관계에 관한 연구

  • 홍정화 (삼성자동차 기술연구소) ;
  • 강신일 (연세대학교 공과대학교 기계설계학과)
  • Published : 1997.12.01
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Abstract

Abnormal intraosseous flow and pressure in trabecular bone could cause various pathological conditions such as osteonecrosis and osteoarthritis. Characteristics of intraosseous fluid flow and pressure generation in porous trabecular bone can be significantly affected by the permeability. Factors which determine the permeability could be the porosity and apparent density of trabecular bone. However, there is little data on the permeability and the relationship among the permeability. porosity, and apparent density of trabecular bone. In this study. the permeability. porosity, and apparent density of human lumbar vertebral trabecular bone were experimentally measured. Also, a power relationship among the permeability, porosity, and apparent density was investigated to understand effects of the porosity and apparent density variations on the permeability of trabecular bone based on Kozeny-Carman equation. A near linear relationship between intraosseous fluid flow and time indicated that the fluid phase flowed through the pores in trabecular bone is governed by the permeability. The permeability of trybecular bone was found to have a significant power relationship with the porosity and apparent density (r: 0.84 and $\textit{p}$< 0.0005). The power relationship could be useful to determine the permeability of trybecular bone after measuring the apparent density and porosity.

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References

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