Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Measurement of Absorption and Scattering Coefficients of Biological Tissues by Time-Resolved Reflectance Method

시간 분해 반사율에 의한 생체조직의 흡수계수와 산란계수 측정

  • Published : 1997.12.01
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Abstract

A non-invasive technique to measure absorption and scattering coefficients was investigated The reflected backscattered light from the surface of phantom and biological tissue was obtained by using a time-correlated single photon counting system in pico-second time domain. The absorption and scattering coefficients were acquired by the time of peak and asymptotic behavior of the time-resolved reflectance curve and agreed well the ones that is obtained with deconvolution method It was found that the approximation method was good for biological medium to calculate optical properties due to its convenience and accuracy.

본 연구에서는 생체조직의 흡수계수와 산란계수를 비침습적으로 측정하는 방법에 관하여 연구하였다. 피코초 영역의 펄스폭을 갖는 레이저광으로 조직을 조사하고 산란반사된 빛을 시간상관 단일 광자 계수법을 이용하여 피코초 시간영역에서 측정하였다. 측정된 시간분해 반사율의 최대치에 이르는 시간 및 나중소멸부분의 점근선의 기울기로부터 계산되는 값과 디컨블루션방법에 의한 곡선맞춤으로 얻은 값을 비교하여 서로 잘 일치함을 확인하였다. 매질의 산란이 커질수록 흡수가 작을수록 근사식은 더 잘 맞으므로 가시광선부터 근적외선의 파장영역에서 흡수에 비해 산란이 매우 큰 생체조직의 광특성을 비침습적으로 측정하는 중요한 방법이 될 수 있다.

Keywords

References

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