Animal cells and systems
- Volume 1 Issue 4
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- Pages.583-587
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- 1997
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- 1976-8354(pISSN)
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- 2151-2485(eISSN)
Chemical Modification of Tryptophan Residue in Bovine Brain succinic Semlaldehyde Reductase
- Hong, Joung-Woo (Department of Genetic Engineering, College of Natural Sciences, Hallym University) ;
- Jeon, Seong-Gyu (Department of Genetic Engineering, College of Natural Sciences, Hallym University) ;
- Bahn, Jae-Hoon (Department of Genetic Engineering, College of Natural Sciences, Hallym University) ;
- Park, Jin-Seu (Department of Genetic Engineering, College of Natural Sciences, Hallym University) ;
- Kwon, Hyeok-Yil (Department of Physiology, College of Medicine, Hallym University) ;
- Cho, Sung-Woo (Department of Biochemistry, College of Medicine, University of Ulsan) ;
- Choi, Soo-Young (Engineering, College of Natural Sciences, Hallym University)
- Published : 1997.12.01
Abstract
Incubation of an NADPH-dependent succinic semialdehyde reductase from bovine brain with N-bromosuccinimide (NBS) resulted in a time-dependent loss of enzyme activity. The inactivation followed pseudo-first-order kinetics with the second-order rate constant of
Keywords
- Brain GABA Shunt;
- Succinic sernialdehyde reductase;
- Chemical modification;
- N-bromosuccinimide;
- Tryptophan residue