비소화성 물질과 칼슘 첨가가 흰쥐의 지질대사에 미치는 영향

Effects of Nondigestable Substances and Calcium on Lipid Metabolism in Rats

  • 이경화 (전남대학교 식품영양학과) ;
  • 최인선 (전남대학교 식품영양학과) ;
  • 이성숙 (전남대학교 식품영양학과) ;
  • 오승호 (전남대학교 식품영양학과)
  • 발행 : 1997.10.01

초록

This study was conducted to investigate the effect of nondigestable substances and calcium such as oligosaccharide, agar, saponin, tannin and calcium on the reduction of lipid status in rats fed high fat diet. In order to make the observation, the lipid content in plasma, liver and the feces, and bile acid excretion were measured of r 4 weeks. the results obtained from this research are as follows. Concentration of total lipid in plasma seemed highest in the control group and were significantly lower in groups oil-gosaccharide, agar and calcium-tannin, compared to the control group. Concentration of total cholesterol in plasma was significantly lower in groups oligosaccharide, agar, calcium and calcium-saponin, compared to the control group. The improvement in lipid status seems to be insignificant with oligosaccharide, showed increase in total bile acids excretion in feces and decrease in total cholesterol in plasma, compared to the control group. These evidence seems to indicate improvement of the plasma lipid status by calcium and agar supplementation.

키워드

참고문헌

  1. 대한의학협회지 v.32 질병 발생의 변화와 식습관 김일순
  2. 한국영양학회지 v.23 비만과 관련된 질환 이홍규
  3. Am. J. Clin. Nutr. v.55 Economic costs obesity Colditz, C. A.
  4. Am. J. Clin. Nutr. v.55 Morbidity of severelv obese subjects Sjostrom, L. V.
  5. J. Nutr. v.121 Oral(n-3) fatty acid supplementation suppresses cytodine production and lymphocyte proliferation : comparison between young and older women Meydan, S. N.;Margom, S. E.;Goldin, W B.;Ladrode, C. A.;Dinarello, C. A.;Gorebach, S. L
  6. Am. J. Clin. Nutr v.45 Monosaturated fatty acid, plasma cholesterol and coronary heart disease Scott, M. G.
  7. J. Lip. Res v.34 Pharmacologic consequences of cholesterol absorption inhibition James, H. H.;Chandler, C. E.;Pellarin, L. D.;bangerter, F. W.;Wilkins, R. W.;Robert, W;Long, C. A.;Mayne, J. T.
  8. 藥局 v.42 コレスラロ-ルの 代謝促進 と排泄 を高ある 藥物 板元史
  9. 脂肪 v.3 コレスラロ-ルの 低下 とりボ蛋白の 變性防止 長野農;北徹
  10. Lancet v.24 Fiber and diabetes Peller, L.
  11. Am. J. Clin. Nutr. v.28 Coronary heart disease and dietary fiber Trowell, H.
  12. Atherosclerosis v.72 The hypocholesterolemic action of the undigestion fraction of soybean protein in rats Michichiro, S.;Yukio, Y.;Katsuko, Y.;Yukio, H.;Takaharu, M.;Minoru, K.
  13. J. Lip. Res. v.31 Dietary influences on serum lipid and lipoproteins Scott, M. G.;Marge, A. D.
  14. 한국영양학회지 춘계심포지움 바람직한 지방산 섭취 형태 장남수
  15. Europ. J Clin. Nutr. v.44 Lipid profiles among fish-jconsuming coastal and non-fish consuming in land population Bulliya, G.;Reddy, K. K.;Reddanna, P.;Kumati, K. S.
  16. Herba Polonica, Toin v.ⅩⅩⅦ Effect of pollen on serum and liver lipid in rat fed on a high lipid diet Samochowiec, L.;Wojcick, J.
  17. Lipids v.26 Implication of steroid saponin and sapogenins in the hypocholesterolemic effect of fenugreek Sauvaire, Y.;Ribes, G.;Baccon, J. C.;Loubatieres-Mariani, M. M.
  18. Lancet v.1 Definitions of fiber Trowell, H. C.
  19. Proceedings of kellog's international symposium on dietary fiber, Chem. Sci(ed.) Dietary fiber, definition and determination Marlett, J. A.
  20. J. Am. Diet. Assoc. v.87 Dietary fiber in the reduction of colon cancer risk Greenwald, P.;Lanza, E.;Eddy, G. A.
  21. Handbook of dietary fiber in human nutrition Fiber in the treatment of hyperlipidemia Jenkins, D. J.. A.;Rainey-Macdonald, C G.;Jenkins, A. L.;Benn, C.;Spiller, G(ed)
  22. Am. J. Clin. Nutr. v.48 Hypocholesterolemic effects of bean products Anderson, J. W.;Gustafson, N. J.
  23. Clin. Sci. v.66 The mechanism of action of guargum in improving glucose tolerance in man Blackburn, N. A.;Redfern, J. C.;Jarjis, H
  24. Am. J. Clin Nutr. v.47 Dietary fiber decreases fasting blood glucose levels and plasma LDL concentration in noninsulin-dependent diabets mellitus patients Hagander, B.;Asp, N G.;Efendic, S.;Nilsson-Ehle, P.;Schersten, B.
  25. J. Am. Diet. Assoc. v.87 Dietary fiber and diabetes: A comprehensive review and practical application Anderson, J. W.;Gustafson, N. J.;Bryant, C. A.;Clark, J. T.
  26. J. Nutr. v.123 Dietary fat and fiber alter large bowel and portal venous volatile fatty acids and plasma cholesterol but not biliary steroids in pigs David, L.T.;Richard, J. I.;Julie, M. C.;Rodney, P. T.;Kathryn, A. J.;Yustinus, M.
  27. Br. J. Nutr. v.42 The role of saponin of lower plasma cholesterol concentration Oakenfull, D. G.;Fenwick, D E.;Hood, R. L.;Topping, D. L.;Illman, R. J.;Storer, G. B.
  28. Br. J Nutr. v.55 A mechanism for the hypocholesterolemic activity of saponins Sidhu, G. S.;Oakenfull, D. G.
  29. 老年醫學 v.21 ラクトオリコ 糖(ネオシュカ-) の 高脂血症 に對 する 效果 泰麗裁;原勉;及川;孝光;山實;信義;島兵;中島久實子;渡部昭;山下光夫
  30. Br. J. Clin. Nutr. v.60 Effect of condensed tannins prepared from leaves of fodder plants on digestive enzymes in vitro and in the intestine of rats Horigome, T.;Kumar, R.;Okamoto, K.
  31. Br. J. Nutr. v.68 Hypercholesterolemic effect of banana(Musa Sapientum L, Var Cavendishii) pulp in the rat fed on a cholesterolcontaining diet Horigome, T.;Sakaguchi, E.;Kishimoto, C.
  32. Lipids v.27 Effects of polyphenolic natural products on the lipid profiles of rats fed high fat diets Yugararu, T.;Tan, B. K.;Teh, M.;Das, N P.
  33. Gut. v.18 Significance of Ca-soap formation for calcium absorption in the rat Gacs, G.;Barltop, D
  34. 茶葉硏究報告 no.71 茶の分析法 池ケ賢次郞;高柳博次;河南豊正
  35. J. Sci. Fd. Agric. v.26 The nutrition and the rapeutic value of tea-A review Stagg, G. V.;Millin, D. J.
  36. J. Am Oil Chem. Soc. v.62 Dry bean tannins: a review of nutritional implications Reddy, N. R.;Pierson, M. D.;Sathe, S. K;Salunkhe, D. K.
  37. Hawk's physiological chemistry(14th ed.) Oser, B. L.
  38. J. Nutr. v.107 Report of the American Institute of Nutrition Ad Hoc Committee on standards for nutritional studies The American Institute of Nutrition
  39. Am. J. Clin. Pathol. v.53 A colorimetric method for determination of total serum lipids based on the sulfo-phospho-vanillin reaction Frings, C. S.;Dunn, R. T.
  40. J. Biol. Chem. v.226 A simple method for the isolation and purification of total lipids from animal tissues Foleh, J.;Lees, M.;Stanley, G H. S.
  41. Clin Chem. v.24 An enzymatic assay for determining free and total cholesterol in tissue Janet, L.;Hoff, D. E.;Davison, L M;Kritchevsky, D.
  42. Clinica Chimica Acta v.64 Determination of faecal bile acids by an enzymatic method Sheltaway, M. J.;Losowsky, M S.
  43. Oil Chemistry v.30 Metabolism of the lipoprotems and lipid Itakura, H.
  44. Fed. Reg v.58 Food Labelling : health and label statements : dietary fiber and cardiovascular disease Food and Administration
  45. Int. J. Obesity. v.11 no.SUP.1 Dietary fiber and lipid metadbolism Kritchevsky, D.
  46. Am. J. Cardiol. v.69 Role of water soluble dietary fiber in the management of elevated plasma cholesterol in healthy subjects Haskell, W. L.;Spiller, G. A;Jensen, L. D.
  47. Am. J. Clin. Nutr. v.39 Interaction of alfafa plant and sprout saponins with cholesterol in vitro and in cholesterol-fed rats Story, J. A.;LePage, S. L.;Petro, M. S.;West, L. G.;Cassidy, M. M.;Lightfoot, F. G;Vahouny, G. V.
  48. Pharmacol. Ther. v.31 Effect of plant sterol on serum lipid and atherosclerosis Pollak, O. J.
  49. Am J. Clin. Nutr. v.33 Effect of dietary saponins on fecal bile acids and neutral steols, plasma lipids and lipoprotein turnover in the pig Topping, D. L.;Storer, G. B.;Calvert, R. J.;Illman, R. J.;Oakenfull, D G.;Weller, R. A.
  50. Proc. Soc. Exp. Biol. Med. v.99 Dietary saponin and plasma cholesterol in the chicken Griminger, P.;Fisher, H.
  51. J. Lip. Res. v.34 Pharmacologic consequences of cholesterol absorption inhibition : alteration in cholesterol metabolism and reduction in p;asma cholesterol concentration induced by the synthetic saponin B-tigogenin cellobioside(cp-88818: tiqueside) Harwood, H. J.;Chandler, C. E.
  52. Science v.204 Watching fat digestion Patton, J. S.;Carey, M. C.
  53. Gerontology v.41 The influence of ingestion of calcium and other soap-formong substances on fecal fat Drenick, E. J.
  54. Br. J. Clin. Nutr. v.71 Study on lipid metabolism in heart and liver of cholesterol and pectin -fed rats Hexeberg, S.;Hexebers, E.;Berge, R A
  55. J. Nutr v.120 The effect of dietary fiber feeding on cholesterol metabolism in rats Nishina, P. M.;Freedland, R A
  56. J. Nutr. v.74 Benefifcial effect pectin in prevention of hypocholesterolemia and increase in liver cholesterol fed rats Wells, A. F.;Ershoff, B. H.