생명과학회지 (Journal of Life Science)

  • 제7권4호
  • /
  • Pages.371-376
  • /
  • 1997
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  • 1225-9918(pISSN)
  • /
  • 2287-3406(eISSN)
한국생명과학회 (Korean Society of Life Science)
권호 표지

흰쥐(SD rats)의 생리활성에 미치는 송엽(松葉) 추출물(PNE)의 영향 I. 혈청중의 지질 및 산소라디칼 대사에 미치는 PNE의 투여효과

Effect of Pine Needle Extract (PNE) on Physiological Activity of SD Rats I. Feeding Effect of PNE on Lipid and Oxygen Radical Metabolisms in Serum of SD rats

  • 최진호 (부경대학교 자연과학대학 식품생명과학과) ;
  • 김동우 (부경대학교 자연과학대학 식품생명과학과) ;
  • 김정화 (부경대학교 자연과학대학 식품생명과학과) ;
  • 김경석 (부경대학교 자연과학대학 식품생명과학과) ;
  • 이종수 (부경대학교 자연과학대학 식품생명과학과)
  • 발행 : 1997.12.01
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초록

This study was edsigne to investgate the effect of pine needle extract (PNE) on lipid adn oxygen radical metabolisms in serum of Sprague-Dawly (SD). Pine(Pinus densiflora Sieb et Zucc.) is one of the popular plant drugs which gas been used as a medicine in Asia. Male SD rats were fed basic (control group) and experimental diets(RGE group) with 0.5 and 1.0% of PNE for 6 weeks. Body weights gain in 0.5-PNE and 1.0-PNE groups were slightly lower than that in control group, but ther is no significant differences brtween these groups. Total energy intake, feed and gross efficiencies showed almost no change in these groups. Total cholesterol and triglyceride (TG) levels in serumof SD rats in .50-PNE and 0.1-PNE froups sho9wed almost no change colpared with control group. Serum LDL-cholesterol levels significantly decreased (12%) in 0.5-PNE group, while serum HDL-cholesterol levels significantly increased(14%) in 1.0-PNE group compared with control group. Malondialdehyde (MDA) and lipid peroxide (LPO) levels in 50-PNE and 0.1-PNE groups were significantly lower (17 and 13%, 24% and 12%, respectively) than those in control group. Superoxide disumutase (SOD) activity in 50-PNE and 0.1-PNE groups significantly increased about 30 to 15% compared with control group. There results suggest that lower LDL-cholesterol and LPO levels, higher HDL-cholsterol level, and higher SOD activity in serum of rats may be effectively modulated by administration of pine needle extract(PNE).

키워드

참고문헌

  1. 原色和漢藥圖鑑(下) 難波恒雄(著)
  2. 韓國食經大典 李盛雨(著)
  3. 한국노화학회지 v.1 no.1 솔잎 첨가식이가 흰쥐의 혈청 지방질 대사에 미치는 영향 김종대;윤태헌;최면;임경자;주진순;이상영
  4. 한국영양식량학회지 v.25 no.3 술입추출물이 고지방식이를 급여한 흰쥐의 혈청과 간장의 지질 조성에 미치는 영향 강윤한;박용곤;하태열;문광덕
  5. 한국영양식량학회지 v.25 no.3 솔잎 추출물이 고지방식이를 급여한 흰쥐의 혈청, 간장의 효소 및 간조직 구조에 미치는 영향 강윤한;박용곤;하태열;문광덕
  6. Mutat. Res. v.347 no.3-4 Study on the antimutafenic effect of pine needle extract Kong, Z.;Liu, Z.;Ding, B.
  7. 한국수산학회지 v.19 no.4 비만 치료식 개발을 위한 기초연구(1). 식물섬우로서 알길산의 비만 억제효과 최진호;임체환;김재연;양종순;최재수;변대석
  8. J. Nutr. v.114 Exercise and detraining :Effect on food intake, adiposity and lipogenesis in Osborne-Mendel rats made by a high fat diet Applegage, E. A.;Upton, D. E.;Stern, J. S.
  9. J. Lipid. Res. v.14 Determination of cholesterol using opthaladehyde Rudel, L. L.;Morris, M. D.
  10. Clin. Chem. v.24 Simultaneous determination of serum cholesterol in high and low density lipoprotein with use of heparin, $Ca^{2+}$ and an anion exchange resin Noma, A.;Nakayama, K. N.;Kita, M.;Okabe, H.
  11. Age. v.12 The effect of food restriction on kidney memgrance structures of aging rats Choi, J. H.;Yu, B. P;
  12. Chemistry and Physics of Lipids v.45 Lipid peroxides and human diseases Yagi, K.
  13. Anal. Biochem. v.42 Reevaluation of assay methods and establishment of kit for superoxide dismutase activity Oynagui, Y.
  14. Principles and procedures of stastics Steel, R. G. D.;Torrie, J. H.
  15. Am. J. clin. Nutr. v.22 Serum sholesterol an dtriglyceride. An epidemiological and pathogenetic interpretation. a12 Schilling, R. J.;Christakis, G.;Orbach, A.;Becker, W. H.