생명과학회지 (Journal of Life Science)

  • 제7권4호
  • /
  • Pages.361-370
  • /
  • 1997
  • /
  • 1225-9918(pISSN)
  • /
  • 2287-3406(eISSN)
한국생명과학회 (Korean Society of Life Science)
권호 표지

미역(Undaria pinnatifida)의 알긴산-첨가 기능성 음료(해조미인)가 흰쥐의 비만 및 생리활성에 미치는 영향

Effect of Alginic Acid-Added Functional Drink(HAEJOMIIN)in Brown Angae(Undaria pinnatifida) on Obesity and Biological Activity of SD Rats

  • 최진호 (부경대학교 자연과학대학 식품생명과학과) ;
  • 김동우 (부경대학교 자연과학대학 식품생명과학과)
  • 발행 : 1997.12.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Sprague-Dawley male rats were fed experimental diet, and also were orally daministerred with 3.0% ultra low viscosity (ULV) sodium alginate-added functional drink(AL-3.0% group : HAEJOMIN), 5.0% polyedxtrose(PD)-added drink(PD-5.0group) and 2.5% polydextrose-added drink(PD-2.5 group) for 8 weeks. Effect of rhese dietary fiber-added functional drinks on body weight, feed and gross efficincies, triglyceride and cholesterol levels, LDL- cholesterol levels, hydroxyl radical and malondialdehyde levels, and superoxide dismutase (SOD) activity in serum of SD rats were evaluated. Administration of AL-3.0 drink and PD-5.0 drink resulted in a marked inhibition in increase of body weight compared with control and PD-2.5 groups for 8 weeks. Inhibition effect in body weight in 3.0% alginic acid-added drink )AL-3.0 froup_ showed a same trend in 5.0% polydextrose(PD)-added drink (PD-5.0 group)(p<0.001). Therefore, it is found that inhibition effects of obesity in 3.0% alginic acid-added drink were higher 2 times than that in same concentration of polydextrose(PD)-added drink. Triglyceride and cholesterol levels in AL-3.0 and PD-5.0 groups significantly decreased to 25$\sim$30% compared with control group(p<0.01$\sim$0.001), but there were no significant differences in these drinks. LDL-cholesterol levels in AL-3.0 group significantly decreased about 15% compared with PD-5.0 group, but atherogenic index in AL-3, 0 group showed a similar trend to that in PD-5.0 group. Hydroxyl radical formations and lipid peroxide(LPO) levels in AL-3, 0 and PD-5.0 groups significantly decreased to 15% and 20%, respectively, compared with control group(p, 0.05$\sim$0.01), but there were no significant differences in these drinks. Superoxide, dismutase(SOD) activity in AL-3.0 group significantly higher (about 255) than those in control and PD-5.0 groups(p<0.01). These results suggest that administration of ULV-sodium alginate-added functional drink(HAEJOMIIN) effectively can not only inhibit obesity, but also can intervent chronic degenerative disease and aging process.

키워드

참고문헌

  1. 한국수산학회지 v.19 no.4 비만치료식 개발을 위한 기초연구 1. 식물섬유로서의 알긴산의 비만억제효과 최진호;임채환;김재연;양종순;최재수;변대석
  2. 한국수산학회지 v.19 no.5 비만치료식 개발을 위한 기초연구 2. 해조류성분의 비만 억제작용 비교 최진호;최재수;변대석;양달선
  3. 한국노화학회지 v.1 no.2 비만억제작용에 미치는 미역의 용량의 존성의 영향1. 체중, 대사체중, 시료 및 에너지 효율에 미치는 영향 최진호;김재일;김일설;최재수;변대석;윤태헌
  4. 한국노화학회지 v.2 no.2 고지방 사료로 유도한 비만 흰쥐의 비만에 미치는 미역성분의 영향 1. 체중, 시료및 에너디효율, 체지방 함량 및 비만지수 김재일;최진호
  5. 한국노화학회지 v.3 no.1 고지방사료로 유도한 흰쥐의 지질대사에 미치는 미역성분의 영향 김재일;김일성;문영실;최진호
  6. 한국노화학회지 v.1 no.2 해조류성분의 노화억제작용에 관한 연구 1. 혈청지질 속의 노화억에작용의 성분으로서 알긴산의 투여효과 최진호;김일성;김재일;휸태헌
  7. 한국수산학회지 v.25 no.3 해조류성분의 노화억제작용에 관한 연구 1. 간장 세포막속의 노화억제작용의 조절성분으로서 알긴산의 투여효과 최진호;김일성;김재일;윤태헌
  8. 한국노화학회지 v.3 no.2 알긴산 첨가 요구르트가 흰쥐의 비만 억제와 생리작용에 미치는 영향 최진호;김재일;김동우;오두환
  9. 제 1회 알긴산국제학술세미나 초록집 성인병과 노화 억제작용에 미치는 해조류성분으로서 알긴산의 투여효과 최진호
  10. 수산식품연구와 과학정보(수산식품 연구소) v.1 no.1 알긴산 첨가 음료가 흰쥐의 비만 및 생리활성에 미치는 영향 최진호
  11. Proceeding of International Symposium on Food Hygiene and Safety Studies on Funcational Property and Satety of Seafood Choi, Jin-Ho
  12. J. Nutr. v.114 Exercise and detraining : Effecton on food intake, adiposity and lipogenesis in Osborne-Mendel rats made obses by a high fat diet Applegate, E. A.;Upton, D. E.;Stern, J. S.
  13. J. Lipid Res. v.14 Determination of cholesterol using opthalaldehyde Rudel, L. L.;Morris, M. D.
  14. Nurochem. Res. v.8 no.4 Biochemical changes of rat brain membaers with aging Calderini, G.;Bonetti, A. C.;Battistella, A.;Brews, F. T.Toffano, G.
  15. Age. v.13 Unsuitability of TBA test as a lipid peroxidation marker due to prostaglandin synthesis in the aging kidney Shoi, J. H.;Yu, B. P.
  16. Chemstry and Physics of Lipids v.45 Lipid peroxides and human diseases Yagi, J.
  17. Chem. J. Biol. v.249 Enzyne catalyzed free radical reactions with nicotinamide adenine nucleotide Chan, P. C.;Bielski, B. H. T.
  18. 한국노화학회지 v.6 no.3 기억 학습장애 동물모델 SAMP8에 미치는 도코사핵사엔산(DHA)의 영향 Ⅱ. SAMP8 뇌의 산소 라디칼 및 그 제거효소에 미치는 DHA의 투여효과 최진호;김동우;김재일;한상섭
  19. Chem. J. B v.244 Superoxide dismutase. An enzymic function for erythrocuprein(hemo cuprein) McCord, J. M.;Fridovch, I.
  20. Anal. Biochem. v.42 Reevaluation of assay methods and establishment of Kit for superoxide dismutase activity Oyanagui, Y.
  21. Principles and procedures of statistics Steel, R. G. D.;Torrie, J. H.
  22. 公開特許公報(A) 乎2-303468(1990년 12월 7일) アルギン酸類飮料及びその製造法 村田克巳;立江신二
  23. Handbook of Geriatric Nutrition Cholesterol metabolism and stherosclerosis in aging Khan, M. A.;Manejwala, A. M.;Hus, J. M.(eds.);Davis, R. L.(eds.)
  24. Bifidobacteria Microflora v.10 no.1 Effect of high cholesterol dite and polydextrose supplementation on the microflota, bacterial enzyme activity, putrefavtive products, volatile fatty acid(VFA) profile, weight, and pH of the feces in healthy volunteers Endo, K.;Kumemur, M.;Nakamura, K.;Fujisawa, T.;Suzuki, K.;Benno, Y.;Mitsuoka, T.
  25. 한국노화학회지 v.5 no.2 식이섬유 첨가 라면의 투여가 흰쥐의 생리작용에 미치는 영향 최진호;김동우;문영실;김재일;이동수;변재형
  26. J. Gerontol. v.40 no.6 Nutritional influences on aging of fischer 344rats I. Physical, Metabolic, and longevity characteristics Yu, B. P.;Masoro, E. J.;McMahan, C. A.
  27. J. Exper. Biol. Med. v.193 Mechanism of food restriction : Protection of cellular homeostasis Yu, B. P.;Lee, D. W.;Maler, C. G.;Choi, J. H.
  28. Age. v.12 The effect of food restriction on kidney membrane structures of aging rats. Choi, J. H.;Yu, B. P.
  29. Age. v.13 Unsuitability of TBA test as a ipid peroxidation marker due to prostaglandin synthesis in the aging kidney Choil, J. H.;Yu, B. P.
  30. Free Rad. Biol. Med. v.18 no.2 Brain synaptosomal aging: free radicals and membrane fluidity Choi, J. H.;Yu, B. P.
  31. Age. v.19 Analysis of lipid composition and hydroxyl radicals in brain membranes of senescence-accelerated mice Choi, J. H.;Yu, B. P.