Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Isolation of S-627(A) and (B) as Candidates of Anticandiosis Agent

생리활성물질 S-627(A)와 S-627(B)의 분리

  • 이상한 (경북대학교 미생물학과) ;
  • 이동선 (경북대학교 미생물학과) ;
  • 서영배 (경북대학교 미생물학과) ;
  • 김종국 (경북대학교 미생물학과) ;
  • 홍순덕 (경북대학교 미생물학과)
  • Published : 1997.09.01
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Abstract

In order to select new anticandiosis agent-producing candidates, we used a modified selection method. Two active fractions designated as S-6279A) and (B) were isolated from the fermentation broth of Streptomycetes sp. S627 which was screened by methanol extraction, diaion HP-20 and silica gel column chromatography (chloroform-me-thanol, and benzene-ethyl acetate), and preparative thin layer chromatography.

수정된 선별법(modified selection method)을 사용하여 candiosis에 대한 새로운 생리활성물질(anticandiosis agent)을 생성하는 미생물을 분리하여Streptomyces sp. S627이라 명명하였으며, 이균의 발효액으로부터 methanol추출, diaion Hp-20, silica gel chromatography, 및 분취용 TLC 등의 방법을 사용하여 물리화학적 특성이 다른 S-637(A)와 S-627(B)을 분리하였다.

Keywords

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