Role of Inflammation in Carcinogenesis

발암과정에서 염증의 역할

  • 이병무 (성균관대학교 약학대학 독성학 교실) ;
  • 이지은 (성균관대학교 약학대학 독성학 교실) ;
  • 김태정 (성균관대학교 약학대학 독성학 교실) ;
  • 조홍태 (성균관대학교 약학대학 독성학 교실)
  • Published : 1997.06.01

Abstract

염증반응이란 우리 신체에 외부 물질이 침입했을 경우 대처하는 정상적인 현상이다. 외부에서 물리, 화학, 생물학적 물질에 노출되었을 경우 혈관이 팽창하고, 비특이적 면역반응이 시작된다. Selectin, integrin, immunoglobulin superfamily와 같은 adhesion molecule에 의해 macrophage 및 neutrophil과 같은 leukocyte의 반응을 촉진하기 위해 exudation이 일어나고 침입 부위에 모여 hyperemia가 발생된다.(Govan 등, 1995)

Keywords

References

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