Abstract
From July 1983 to December 1993, total 112 consecutive mitral valve replacements in 107 patients were performed in patient with mitral valvular abnormalities. To estimate the risk factor related to operative death, all patient's perioperative data were reviewed retrospectively. Except 20 patients received concomitant aortic valve replacement and 2 patients had incomplete data, 85 patients were included in this study. Mean age were $37.3\pm$ 13.1 years ranging from 13 to 72 years. Thirty-seven patients were male and fourty-eight patients were female. Mean follow-up durations were $51.1\pm33.8$ months ranging from 6 months t 11 years. Patients in this study showed improvement in mean NYHA functional clssification, from $3.02\pm0.73$ to 1 $78\pm0.55,$ and also in cardiothoracic ratio, from 0.61 $\pm0.09$ to $0.58\pm0.08$ at 6 months follow-up after operation. Operative complications were detected in 23 patients(27.1 %) and common postoperative complications were rhythm disturbance in 7 cases, pulmonary complications in 6 cases and low cardiac output syndrome in 6 cases. Early mortality was 10.6%(n=9) and the most common cause of death was a congestive heart failure due to low cardiac output syndrome. Main cause of our higher operative mortality than other study was that operative mortality in the initial period of our mitral surgery was high(5 operative deaths among 19 mitral valve replacement from July 1983 to December 1985). Actuarial survival was 80.8% at 5 years, 71.8% at 11 years including operative deaths. Actuarial freedom from anticoagulant-related bleeding was 85.3% at 5 years, 78.3% at 11 years. 95.1% at 5 years and 88.8% at 11 years among the patient in this study were free from thromboembolism, and 97.5% at 5 years and 75.1% at 11 years were free from reoperation. Preoperative cardiothoracic ratio and patient's age were statistically significant operative risk factors.
1983련 7월부터 1993년 12월까지 승모판막 질환을 가진 107명의 환자에게 112예의 승모판막 치환술을 시행하였다. 승모판막 치환술과 관련된 수술 위험 인자를 평가하기 위하여 환자의 수술 전후 기록들 을 분석하였다. 107명의 환자들 중 대동맥판을 함께 치환한 20명과수술 전후의 기록이 불완전한 2명을 제외한 환자 85명을 대상으로 하였다. 나이는 평균 $37.3\pm$ 13.1세로 13세에서 72세까지의 분포를 보였으며 성 별 분포는 남자가 37예, 여자 48예였다. 평균 추적관찰기간은 51.1 $\pm33.8$ 개월로 6개월에서 11년까지 였다. 수술후 6개월에 환자들은 NYHA 기능분류가 술전 평균 $3.02\pm0.73에서$ 1.78 $\pm0.55로,$ 심흉곽비 또한 술전 평균 0.61 $\pm0.09에서$ $0.58\pm0.08로$ 개선되었다. 수술후 합병증은 23예(27.1%)에서 발생하였고 부정 맥 7예,호흡기 합병증 6예와 저심박출증 6예 등이 있었다. 수술사망은 9예(10.6%)에서 발생하였는데 가장 흔한 사망의 원인은 저심박출증으로 인한 울혈성 심부전이었다. 본 연구의 수술사망이 비교적 높았던 주된 요인으로는 초기 수술에서의 수술사망이 많았던 점을 지적할 수 있다( 1983년 7월부터 1985년 12월까지의 수술 19\ulcorner 중 5예의 수술사망이 있었다 ). 수술사망을 포함한 생존을(Actuarial survival)은 5년에 80.8%, 11년에 71.8%였고 항응고제와 관계된 출혈 자유율은 5년에 85.3% 11년에 78.3%였으며 혈전색전증의 자유율은 5년에 95.1% 11년에 88.8%, 재수술로부터의 5년과 11년 자유율도 각각 97.5%와 75.1%였다. 술전심흉곽비와 수술 당시의 환자의 연령이 통계적으로 의의 있는 수술 위험 인자로 분석되 었다.
