Journal of the East Asian Society of Dietary Life (동아시아식생활학회지)

The East Asian Society of Dietary Life (동아시아식생활학회)
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Effect of Ethanol Pretreatment on the Serum and Liver Xanthine Oxidase Activity in Bromobenzene-Treated Rats

Ethanol을 전처치한 흰쥐의 간 및 혈청 Xanthine Oxidase 활성에 미치는 Bromobenzene의 영향

  • 윤종국 (계명대학교 자연과학대학 공중보건학과) ;
  • 임영숙 (대구공업전문대학 식품영양과)
  • Published : 1997.03.01
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Abstract

To evaluate the effect of ethanol pretreatment on the liver and serum xanthine oxidase(XO) activity, the bromobenzene(40mg/kg body wt., i.p.) was orally given 3 times daily to the Sprague-Dawley male rats pretreated with 5% ethanol throughout 2 months. Bromobenzene treated rats pretreated with ethanol showed the more decreased activity of serum and liver XO, and lower value of V than those of only bromobenzene treated rats. Bu the bromobenzene treatment, ethanol pretreated rats showed the more decreased levels of serum alanine aminotransferase activity and liver weight/bo여 weight(%), and decreased degree of liver damage on histopathological observation than the control group.

Keywords

References

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