3-D Flow Analysis of Blood and Blood Substitutes in a Double Branching Model

이중 분지관내 혈액 및 혈액대용유체의 3차원 유동해석

  • Suh, Sang-Ho (Department of Mechanical Engineering, Soong Sil University) ;
  • Yoo, Sang-Sin (Department of Mechanical Engineering & Design, HanKuk Aiation University) ;
  • Roh, Hyung-Woon (Department of Mechanical Engineering, Soong Sil University)
  • Published : 1997.06.01

Abstract

The three-dimensional flow analysis using the finite volume method is presented to compare the steady flow characteristics of blood with those of blood substitutes such as water and aqueous polymer solution in an idealized double branching model. The model is used to simlllate the region of the abdominal aorta near the celiac and superior mesenteric branches. Apparent viscosities of blood and the aqueous Separan solution are represented as a function of shear rate by the Carreau model, Water and aqueoiu Separan AP-273 500wppm solution are frequently used as blood substitutes in vitro experiments. Water is a typical Newtonian fluid and blood and Separan solution are non-Newtonian fluids. Flow phenomena such as velocity distribution, pressure variation and wall shear stress distribution of water, blood and polymer solution are quite different due to differences of the rheological characteristics of fluids. Flow phenomena of polymer solution are qualitatively similar to those of blood but the phenomena of water are quite different from those of blood and polymer solution. It is recommended that a lion-Newtonian fluid which exhibits very similar rheological behavior to blood be used in vitro experiments. A non-Newtonian fluid whose rheological characteristics are very similar to those of blood should be used to obtain the meaninylll hemodynamic data for blood flow in vitro experiment and by numerical analysis

Keywords

References

  1. British Geart J. v.28 Localization of Atherma: Tehory Based on Boundary Layer Separtion J. A. Fox;A. E. Hugh
  2. Mass Transger Phenomena in Biological Systems in Biomaterials K. H. Keller;Stark, L(ed.);Agarwal, G(Ed.)
  3. Proc. R. Soc. B v.177 Atheroma and Arterial Wall Shear: Observation, Correlation and Proposal of a Shear Dependent Mass Transfer Mechanism for Atherogenesis C. G. Caro;J. M. Fitz-Gerald;R. C. Schroter
  4. A Ciba Foundation Symp. Response of the Arterial Wall to Certain Physical Factors. Atherogenesis: Initiating Factors D. L. Fry
  5. J. Biomechanics v.15 no.7 Maseurement and Calculatios of Laminar Flow in a Ninety Degree Bifurcation D. Liepsch;S. Moravec;A. K. Rastagi;N. S. Vlachos
  6. Biorheolgy v.20 Flow Investigation in a Model of a Three Dimensional Human Artery with Newtonian and Non-Newtonian Fluids(Part 1) D. Liepsch;S. Moravec
  7. ASME J. Biomech. Eng. v.107 Experimental Investigation of Branch Flow Ratio, Angle and Reynolds Number Effects on the Pressure and Flow Fields in Arterial Branch Models Y. I. Cho;L. Back;D. W. Crawford
  8. Hemodynamics W. R. Milnor
  9. McDonald's Blood Flow in Arteries W. W. Nichols;M. F. O'Rourke
  10. J. Biomechanics v.16 no.9 Comparison of Steady an Pulsatile Flow in a Double Branching Arterial Model R. J. Lutz;L. Hsu;A. Menawat;J. Zrubek;K. Edwards
  11. Ph. D. Thesis, Drexel University A Study of Pulsatile Flows sith Non-Newtonian Viscosity of Blood in Large Arteries R. K. Banerjee
  12. Automedia v.15 Aspects of Non-Newtonian Blood Flow in Prosthetic Valve Studies G. D. Tansley
  13. Ph. D. Thesis, University of Wisconsin P. J. Carreau
  14. Proc. of the 6th International Symp. on Transport Phenomena and Dynamics of Rotating Machinery v.2 Flow Characteristics of Non-Newtonian Fluids in the Stenotic and Bifurcated Tubes S.S. Yoo;S. H. Suh
  15. AIAA J. v.21 Numerical Study of Turbulent Flow Past an Airfoil with Trailing Edge Separation C. M. Rhie;W. L. Chow
  16. SIAM. J. Numer. Anat. v.5 no.3 Iterative Solution of Implicit Approximations of Multidimensional Partial Differential Equations H. L. Stone
  17. KSME Journal v.10 no.2 Numerical Simulation of Flows of Non-Newtonian Fluids in the Stenotic and Bifurcated Tubes S. S. Yoo;S. H. Suh;H. W. Roh