Inhibitory Effects of Ginseng Total Saponin on Methamphetamine-induced Striatal Dopamine Increase in Mice

  • Oh, Ki-Wan (Department of Pharmacology, College of Pharmacy, Chungbuk National University) ;
  • Kim, Hack-Seang (Department of Pharmacology, College of Pharmacy, Chungbuk National University) ;
  • Wagner, George-C. (Department of Psychology, Busch Campus, Rutgers University)
  • Published : 1997.10.01

Abstract

In conclusion, biochemical analysis revealed that GTS inhibited the methamphetamine-induced DA increase and the methamphetamine-induced DOPAC decrease in the mouse striatum. These results indicate that GTS could modulate the methamphetamine-induced striatal dopaminergic neuronal systems.

Keywords

References

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