Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Studies on the Synthesis and in vitro anti-Tumor Activity of Dihydroberberine Derivatives

  • Published : 1997.10.01
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Abstract

Three types of dihydroberberine derivatives such as spirobenzylisoquinoline, benzindenoazepine and cyclopropanated quinolizine species were synthesized from dihydroberberine for the investigation on their anti-tumor activity. Among them, cyclopropanated quinolizine species were more effective than spirobenzylisoquinoline and benzindenoazepine against P-388 and L-1210 leukemia cell.

Keywords

References

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