Archives of Pharmacal Research
- 제20권2호
- /
- Pages.148-154
- /
- 1997
- /
- 0253-6269(pISSN)
- /
- 1976-3786(eISSN)
Chlorogenic Acid, an Antioxidant Principle from the Aerial Parts of Artemisia iwayomogi that Acts on 1,1-Diphenyl-2-picrylhydrazyl Radical
- Kim, Soon-Shin (College of Pharmacy, Kyungsung University) ;
- Lee, Chung-Kyu (College of Pharmacy, Kyungsung University) ;
- Sam, Sik-Kang (Natural Products Research Institute, Seoul National University) ;
- Jung, Hyun-Ah (Department of Food and Life Science, Pukyong National University) ;
-
Choi, Jae-Sue
(Department of Food and Life Science, Pukyong National University)
- 발행 : 1997.04.01
초록
The antioxidant activity of Artemisia iwayomogi was determined by measuring the radical scavenging effect on 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical. The methanol extract of A. iwayomogi showed strong antioxidant activity, and thus fractionated with several solvents. The antioxidant activity potential of the individual fraction was in the order of ethyl acetate > n-butanol > water > chloroform > n-hexane fraction. The ethyl acetate and n-butanol soluble fractions exhibiting strong antioxidant activity were further purified by repeated sitica get and Sephadex LH-20 column chromatography. Antioxidant chlorogenic acid was isolated as one of the active principles from the n-butanol fraction, together with the inactive components, 1octacosanol, scopoletin, scopolin, apigenin
키워드