Archives of Pharmacal Research
- Volume 20 Issue 1
- /
- Pages.85-87
- /
- 1997
- /
- 0253-6269(pISSN)
- /
- 1976-3786(eISSN)
Cytotoxic Constituents of Sorbaria sorbifolia var. stellipila
- Kim, Dae-Keun (College of Pharmacy, Sung Kyun Kwan University) ;
- Choi, Sang-Hoon (Korea Research Institute of Chemical Technology) ;
-
Lee, Jung-Ock
(Korea Research Institute of Chemical Technology)
;
-
Ryu, Shi-Yong
(Korea Research Institute of Chemical Technology)
;
- Park, Dae-Kyu (Chosun Pharm and Trading Co. Institute of Life Science Research) ;
- Shin, Dae-Hee (Chosun Pharm and Trading Co. Institute of Life Science Research) ;
- Jung, Jee-Hyung (College of Pharmacy, Pusan University) ;
- Pyo, Suhk-Keung (College of Pharmacy, Sung Kyun Kwan University) ;
-
Lee, Kang-Ro
(College of Pharmacy, Sung Kyun Kwan University)
;
- Zee, Ok-Pyo (College of Pharmacy, Sung Kyun Kwan University)
- Published : 1997.02.01
Abstract
The activity-guided fractionation upon the MeOH extract of the aerial parts of Sorbaria sorbifolia var. stellipila led to the isolation of two cucurbitacin-compounds, cucurbitacin D and cucurbitacin F, as active principles. Two compounds were shown to exhibit significant cytotoxicity against cultured human tumor cell lines, A-549, SK-OV-3, SK-MEL-2, XF-498, and HCT 15.