Parasites, Hosts and Diseases
- Volume 35 Issue 3
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- Pages.181-188
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- 1997
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- 2982-5164(pISSN)
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- 1738-0006(eISSN)
Effects of Cryptospoyidium bnileyi infection on the bursa of Fabricius in chickens
닭에 있어서 닭와포자충 감염이 파브리시우스낭에 미치는 영향
- Lee, Jae-Gu (Bio-Safety Research Institute, Chonbuk National University) ;
- Kim, Hyeon-Cheol (Bio-Safety Research Institute, Chonbuk National University) ;
- Park, Bae-Geun (Bio-Safety Research Institute, Chonbuk National University)
- Published : 1997.09.01
Abstract
In order to clarify the effect of cryptosporidiosis on immune response, histopathological changes associated with experimentally occurring bursal cryptosporidiosis in chickens were chronologically observed as the first step. A total of 150 2-day-old chickens was each inoculated orally with a single dose of 5 × 105 Cryptospori,mum bailevi oocysts. The chickens showed a normal profile of oocyst shedding in droppings. The bursa indices throughout the experimental period indicated negligible reactions. Numerous cryptosporidia occurred in the microvillous border of bursal epithelium between days 4 and 16 postinoculation (PI). Appearance of the most mast cells was followed by a dramatic loss of the protozoa in the bursa of Fabricius (BF). The distribution of the coccidium coincided with heterophil infiltration in the epithelium and adjacent lamina propria. The histopathological lesion was marked diffuse chronic superficial purulent bursitis with heterophil infiltration in the epithelium and adjacent lamina proprla and mucosal epithelial hyperplasia. These results suggest that the bursitis may induce immunosuppressive effect.
닭에 있어서 닭와포자충 갉염이 면역반응에 미치는 영향을 규명하기 위한 기초적 연구리 일환으로 파브리시우스낭의 병리조직학적 소견을 경시적으로 조사하고자 150마리의 2일령 SPF 병아리 (Drkalb-Warren, Sex-Sal-Link)에 닭와포자충의 오오시스트