The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Experimental study on the effects of Boyanghwanoh-tang(補陽還五湯) on blood pressure and hyperlipidemia

고혈압(高血壓) 및 고지혈증(高脂血症)에 대(對)한 보양환오탕(補陽還五湯)의 실험적(實驗的) 연구(硏究)

  • Jung, Woo-Sang (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Ko, Chang-Nam (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Cho, Ki-Ho (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Young-Suk (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Bae, Hyung-Sup (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Lee, Kyung-Sup (Department of Circulatory Internal Medicine, College of Oriental Medicine, Kyung Hee University)
  • 정우상 (경희대학교 한의과대학 심계내과학교실) ;
  • 고창남 (경희대학교 한의과대학 심계내과학교실) ;
  • 조기호 (경희대학교 한의과대학 심계내과학교실) ;
  • 김영석 (경희대학교 한의과대학 심계내과학교실) ;
  • 배형섭 (경희대학교 한의과대학 심계내과학교실) ;
  • 이경섭 (경희대학교 한의과대학 심계내과학교실)
  • Published : 1997.12.30
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Abstract

In order to study the effects of Boyanghwanoh-tang(補陽還五湯) on blood pressure and hyperlipidemia, experimental study was performed on Hypertension in normal rats, SHR, and on Hyperlipidemia induced by Triton WR-1339 and 2% cholesterol Fed-diet in normal rats. Also the level of Total cholesterol, Triglyceride, LDL-cholesterol, HDL-cholesterol, Phospholipid were measured. The results are summarized as follows : 1. After Boyanghwanoh-tang(補陽還五湯) was given to normal rats and SHR, the results showed that inhibitory effects on blood pressure were not significant but exitory effects on heart beat were significant. 2. In the model of hyperlipidemia Rats induced by 2% Cholesterol Fed-Diet, Boyanghwanoh-tang(補陽還五湯) had significantly decreasing effects on Total cholesterol, Triglyceride, LDL-cholesterol, Phospholipid level in serum but no significantly increasing effects on HDL-cholesterol level in serum. 3. In the model of hyperlipidemia Rats induced by Triton WR-1339, Boyanghwanoh-tang(補陽還五湯) had significantly decreasing effects on LDL-cholesterol, Phospholipid level in serum and significantly increasing effects on HDL-cholesterol level in serum but there were not significantly decreasing effects on Total cholesterol, Triglyceride. These results show that Boyanghwanoh-tang(補陽還五湯) has significantly inhibitory effects on hyperlipidemia and thal it could be clinically applied for hyperlipidemia.

Keywords

References

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