죽력(竹瀝)이 T-lymphocytes 및 복강(腹腔) Macrophage에 미치는 영향(影響)

Effect of Bambusae Caulis in Liquamen on T-lymphocytes and Peritoneal Macrophages

  • 발행 : 1997.12.30

초록

The purpose of this research was to investigate effects of Bambusae Caulis in Liquamen(BCL) on T-lymphocytes and peritoneal macrophages in mice. The apoptosis and subpopulation of T-lymphocytes were tested using a flow cytometer. The phagocytic activity of mouse peritoneal macrophage was tested using a luminometer. Nitric oxide production was tested using a Griess reagents. BCL induced T-lymphocytes apoptosis. BCL increased $T_H$ cells population and decreased $T_C$ cells population of T-lymphocyte, but did not affect splenocytes subpopulation. BCL increased nitric oxide production and phagocytic activity of peritoneal macrophage in mice. These results suggest that BCL regulates the immune system in consequence of an increase in helper T cell population and macrophages activation.

키워드

참고문헌

  1. 뇌졸증의 예방과 치료(현대의학-한의학 결합) 김종석(譯)
  2. 원색임상본초학 辛民敎
  3. 대한약전외 한약규격집 보건사회부
  4. Proc. Natl. Acad. Sci. USA. v.75 Planning for lymphocytes: A method for cell selection Wysocki, L.J.;Sato, V.L.
  5. J. Immunol. v.120 Characterization of lymphocyte-activating factor(LAF) produced by the macrophage cell line P388D1 Mizel, S.B.;Openheim, J.J.;Rosensteich, D.L.
  6. J. Immunol. Methods v.139 Radid and simple method for mesuring thymocyte apoptosis by propidium iodide staining and flow cytometry Nicoletti, I.;Migliorati, G.;Pagliacci, M.C.;Grignani, F.;Riccardi, C.A.
  7. J. Immunol. Methods v.112 Measurement of phagocyte chemiluminenscence in a microtiter plate format Blair, A.L.;Cree, I.A.;Beck, J.S.;Hating, M.J.G.
  8. J. Immunol. Methods v.174 Chemiluminenscence and nitrite determinations by the MALU macrophage cell line Boudard, F.;Vallot, N.;Cabaner, C.;Bastide, M.
  9. Infect. Immunity v.59 no.9 Killing of Plasmodium falciparum in vitro by nitric oxide derivatives Rockett, K.A.;Awburn, M.M.;Cowden, W.B.;Clark, I.A.
  10. 中藥心法 程紹恩(外 3人)
  11. 新編中藥大辭典 新文豊出版公司
  12. 東醫兒科學 具本泓(外 4人)
  13. 中醫雜病論治 戴錦成
  14. 黃帝內經素問靈樞譯解 楊維傑
  15. 中醫辨證學 柯雪帆
  16. 中醫學槪論 孟景春;周仲瑛
  17. 일반병리학 김상호(外 4인)
  18. 기본병리학 이중달
  19. 병리학 대한병리학회
  20. 그림으로 설명한 병리학 이중달
  21. 中醫病因病耭學 宋鷺氷
  22. 내과학 이문호(외 2인)
  23. 備急千金要方 孫思邈
  24. Immunol. Today. v.11 Cellular signaling in programmed cell death(apoptosis) McConkey, D.J.(et al.)
  25. Nature v.337 Antibodies to CD/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures Smith, C.A.;Williams, G.T.;Kingston, E.;Jenkinson, J.;Owen, J.J.T.
  26. J. Exp. Med. v.181 Reduction in mitochodrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo Zamzami, N.;Marchetti, P.;Castedo, M.;Zanin, C.;Vayssiere, J.L.;Petit, P.X.;Kroemer, G.
  27. J. Exp. Med. v.182 Prevention of agerelated T cell apoptosis defect in CD2-fas-transgenic mice Zhou, T.;Edwards, C.K.;Mounts, J.D.
  28. FASEB J. v.6 Nitric oxide as a secretory product of mammalian cells Nathan, C.
  29. Nature v.336 Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the Brain Garthwaite, J.;Charles, S.L.;Chess-Williams, R.
  30. Biochem. Biophysic. Res. Commun. v.157 A cytotoxic and activated macrophage effector molecule Hibbs, J.B.;Taintor, R.R.;Vavrin, Z.;Rachlin, E.M.
  31. FASEB Journal v.7 Niric oxide sythesis inhibition induced leukocyte adhesion via superoxide and master cell Kubes, P.;Kanwar, S.;Niu, X.;Gaboury, J.P.
  32. Nature v.327 Nitric oxiderelease accounts for the biology activity of endothelium derived relaxing factor Palmer, P.M.J.;Ferrige, A.G.;Monacada, S.
  33. Nature v.349 Endogenous nitric oxide release required for long term synatic depression in the cerebellum Shibuki, K.;Okada, D.
  34. J. Exp. Med. v.169 Nitric oxide macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells Stuehr, D.J.;Nathan, C.F.
  35. Critical Care Medicine v.20 Nitric oxide systhesis serves to reduce hepatic damage during acute murine endotoxemia Harbrecht, B.G.;Billiar, T.R.;Stadler, T.;Demetris, A.J.;Ochoa, J.B.;Curran, R.D.;Simmons, R.L.
  36. 그림으로 본 면역학 하대유(외 25인)