Development of Biologically Active Compounds from Edible Plant Sources-I. -Isolation of Major Components from the Tuber of Ipomoea batatas Lam.-

식용 식물자원으로부터 활성물질의 탐색-I. -고구마(Ipomoea batatas Lam.) 괴근 주요성분의 분리-

The MeOH extracts obtained from the tuber of Ipomoea batatas Lam. were solvent-fractionated with EtOAc, n-BuOH, and $H_2O$, respectively. From EtOAc fraction four different compounds were isolated through the repeated silica gel column chromatographies. From not only the results of NMR and MS data but also the adaptation of hydrolysis, methylation, and acetylation, the chemical structures of compounds were elucidated as resin glycoside, simonin I, ${\beta}-sitosterol$, and two kinds of unsaturated fatty acids.

고구마 괴근을 MeOH 수용액으로 추출하고, 얻어진 추출물을 EtOAc, n-BuOH 및 물로 용매분획하였다. EtOAc 분획에 대하여 column chromatography를 반복하여 4종의 화합물을 분리하였다. 각 화합물의 화학구조를 NMR, MS 등 스펙트럼 데이터의 해석 및 가수분해, 메칠화 및 아세칠화반응을 적용하여, 수지 배당체, simonin I, ${\beta}-sitosterol$ 및 2종의 불포화지방산 화합물로 구명하였다.