Journal of Pharmaceutical Investigation
- Volume 27 Issue 1
- /
- Pages.15-22
- /
- 1997
- /
- 2093-5552(pISSN)
- /
- 2093-6214(eISSN)
Transvaginal Delivery of Luteinizing Hormone-Releasing Hormone Using Bioadhesive Hydrogel
생체막점착성 하이드로겔을 이용한 황체형성호르몬 유리호르몬의 질점막 수송
- Han, Kun (College of Pharmacy, Chungbuk National University) ;
- Park, Hee-Beom (College of Pharmacy, Chungbuk National University) ;
- Park, Jeong-Sook (College of Pharmacy, Chungbuk National University) ;
- Chung, Youn-Bok (College of Pharmacy, Chungbuk National University)
- Published : 1997.03.20
Abstract
The mucosal route of administration(nasal, buccal, conjunctival and vaginal) has recently been considered as an alternative to parenteral delivery for many peptide drugs because enzymatic degradation of these agents may be partly avoided. The objective of these study was to establish the optimal mucosal administration dosage form of
Keywords
- LHRH;
- $[D-Ala^6]LHRH$;
- Medium chain fatty acid;
- Peptidase inhibition;
- Polycarbophil hydrogel;
- Bioavailability