생약학회지 (Korean Journal of Pharmacognosy)
- 제28권4호
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- Pages.215-224
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- 1997
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Gamijiya-tang Decreases the Dimethylnitrosamine-Induced Hepatic Fibrosis in the Rats
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Ma, Jin-Yeul
(Department of Herbal Medicine, Korea Institute of Oriental Medicine) ;
- Yang, Jai-Man (College of Veterinary Medicine, Seoul National University) ;
- Nam, Jeong-Seok (College of Veterinary Medicine, Seoul National University) ;
- Che, Jeong-Hwan (College of Veterinary Medicine, Seoul National University) ;
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Cheon, Won-Kyung
(Department of Herbal Medicine, Korea Institute of Oriental Medicine) ;
- kim, Nam-Joo (Jamsil Clinic for Oriental Medicine) ;
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Ko, Byoung-Seob
(Department of Herbal Medicine, Korea Institute of Oriental Medicine) ;
- Park, Kap-Joo (Department of Herbal Medicine, Korea Institute of Oriental Medicine) ;
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Lee, Yong-Soon
(College of Veterinary Medicine, Seoul National University) ;
- Kyu, Yong-Jung (Department of Herbal Medicine, Korea Institute of Oriental Medicine)
- 발행 : 1997.12.30
초록
Gamijiyu-tang (GJT) described originally in the Dong Eui Bo Gam, a traditional reference for oriental medicine in the Korea, has been clinically used for treatment of chronic liver disease. In order to evaluate scientifcally a hepatoprotective effect of GJT in the liver fibrotic disease, the present study investigated how GJT improves a hepatic function in the dimethylnitrosamine (DMN)-treated rat. DMN treatment caused a significant increase of relative liver weight to the body at 28 days after DMN induction. Administration of with a clinical dose decreased significantly the sAST level