Natural Product Sciences

  • 제3권1호
  • /
  • Pages.42-48
  • /
  • 1997
  • /
  • 1226-3907(pISSN)
  • /
  • 2288-9027(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

Alkaloids from The Roots of Tabernaemontana Macrocarpa Jack

  • Husain, Khairana (Department of Chemistry, University Kebangsaan Malaysia) ;
  • Said, Ikram M. (Department of Chemistry, University Kebangsaan Malaysia) ;
  • Din, Laily B. (Department of Chemistry, University Kebangsaan Malaysia) ;
  • Takayama, Hiromitsu (Faculty of Pharmaceutical Sciences, Chiba University) ;
  • Kitajima, Mariko (Faculty of Pharmaceutical Sciences, Chiba University) ;
  • Aimi, Norio (Faculty of Pharmaceutical Sciences, Chiba University)
  • 발행 : 1997.06.01
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초록

The roots of Tabernaemontana macrocarpa Jack (Apocynaceae) yielded nine indole alkaloids which were identified as coronaridine (2), voacangine hydroxy-indolenine (3), 3-oxo-coronaridine (4), 19-R-heyneanine (7), coronaridine pseudoindoxyl (8) and voacangine pseudoindoxyl (9) while 3-(2-oxopropyl)-coronaridine (1), 3-(2-oxopropyl)-coronaridine-pseudoindoxyl (5) and 3-(2-oxopropyl)-voacangine-pseudoindoxyl (6) were isolated as artefacts formed during the isolation process. All of the alkaloids were identified by spectroscopic methods $(UV,\;MS,\;^1H-NMR\;&\;^{13}C-NMR)$ and in comparison with the literature data.

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