Natural Product Sciences
- 제3권1호
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- Pages.59-70
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- 1997
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- 1226-3907(pISSN)
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- 2288-9027(eISSN)
Inhibitory Effects of Herbal Extracts on CINC-1 Induction in LPS-Stimulated Rat Kidney Epithelioid NRK-52E cells
- Ha, Joo-Young (College of Pharmacy, Chungbuk National University) ;
- Kim, Young-Ki (College of Pharmacy, Chungbuk National University) ;
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Lee, Kyong-Soon
(College of Pharmacy, Chungbuk National University) ;
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Min, Kyung-Rak
(College of Pharmacy, Chungbuk National University) ;
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Kim, Young-Soo
(College of Pharmacy, Chungbuk National University)
- 발행 : 1997.06.01
초록
A rat chemokine, cytokine-induced neutrophil chemoattractant-1 (CINC-1) has chemotactic and activating properties to neutrophils. Rat kidney epithelioid NRK-52E cells contained 4 ng/ml of ClNC-1 as a basal level and their CINC-1 production was significantly increased by stimulation with lipopolysaccharide (LPS) of E. coli. Maximal induction of ClNC-1 was 58 ng/ml when 3