The Korean Journal of Physiology and Pharmacology
- 제1권6호
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- Pages.775-781
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- 1997
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
고양이 허파에서 산소재유입 손상을 결정하는 저산소증의 정도
Determinant Role of the Severity of Hypoxia in the Induction of Reoxygenation Injury in Cat Lung
- Nam, Hyun-Jung (Department of Physiology, Korea University College of Medicine) ;
- Kim, Yoo-Kyung (Department of Physiology, Korea University College of Medicine) ;
- Hong, Seung-Kil (Department of Physiology, Korea University College of Medicine) ;
- Na, Heung-Sik (Department of Physiology, Korea University College of Medicine)
- 발행 : 1997.12.21
초록
Although reoxygenation is the best way to salvage hypoxic tissues, reduced oxygen species (ROS) generated during reoxygenation are blown to cause further tissue injuries and the induction of heat shock proteins (HSPs). The present study was undertaken to determine any causal relationship between the severity of hypoxia and the opposite outcomes, either beneficial or detrimental, of the subsequent reoxygenation by measuring the HSP72. To this aim, one group (6 male cats,