The Korean Journal of Physiology and Pharmacology
- 제1권6호
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- Pages.639-645
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- 1997
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
중추에서 혈압과 심박수 조절에 관여하는 후시상하부 콜린성 수용체의 일차적인 역할
Primary Role of Posterior Hypothalamic Cholinergic Receptors in Central Regulation of Blood Pressure and Heart Rate in Rats
- 김성윤 (가톨릭대학교 의과대학 약리학교실) ;
- 성기욱 (가톨릭대학교 의과대학 약리학교실) ;
- 고현철 (한양대학교 의과대학 약리학교실) ;
- 이상복 (가톨릭대학교 의과대학 약리학교실)
- Kim, Seong-Yun (Department of Pharmacology, Catholic University Medical College) ;
- Sung, Ki-Wug (Department of Pharmacology, Catholic University Medical College) ;
- Koh, Hyun-Chul (Department of Pharmacology, College of Medicine, Hanyang University) ;
- Lee, Sang-Bok (Department of Pharmacology, Catholic University Medical College)
- 발행 : 1997.12.21
초록
The purpose of the present study is to determine the role of muscarinic cholinergic receptors of posterior hypothalamus in the central blood pressure regulation when respiration is controlled. In anesthetized and artificially ventilated rats, vasodepressor response was evoked by injection of L-glutamate(10 nmol) neuroexcitatory amino acid into the posterior hypothalamic area. The injection of
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