The Korean Journal of Physiology and Pharmacology
- 제1권6호
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- Pages.603-611
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- 1997
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
흰쥐의 운동유발전위에 대한 전정신경핵과 연수망상핵의 역할
Role of the Vestibular and Medullary Reticular Neuclei for the Motor Evoked Potentials in Rats
-
이문영
(원광대학교 의과대학 생리학교실) ;
- 이성호 (원광대학교 의과대학 생리학교실) ;
-
김재효
(원광대학교 의과대학 생리학교실) ;
-
박병림
(원광대학교 의과대학 생리학교실) ;
-
김민선
(원광대학교 의과대학 생리학교실)
-
Lee, Moon-Young
(Department of Physiology, Wonkwang University School of Medicine) ;
- Lee, Sung-Ho (Department of Physiology, Wonkwang University School of Medicine) ;
-
Kim, Jae-Hyo
(Department of Physiology, Wonkwang University School of Medicine) ;
-
Park, Byung-Rim
(Department of Physiology, Wonkwang University School of Medicine) ;
-
Kim, Min-Sun
(Department of Physiology, Wonkwang University School of Medicine)
- 발행 : 1997.12.21
초록
The motor evoked potentials (MEPs) have been advocated as a method of monitoring the integrity of spinal efferent pathways in various injury models of the central nervous system. However, there were many disputes about origin sites of MEPs generated by transcranial electrical stimulation. The purpose of present study was to investigate the effect of major extrapyramidal motor nuclei such as lateral vestibular nucleus (VN) and medullary reticular nucleus (mRTN) on any components of the MEPs in adult Sprague-Dalwey rats. MEPs were evoked by electrical stimulation of the right sensorimotor cortex through a stainless steel screw with 0.5mm in diameter, and recorded epidurally at T9 - T10 spinal cord levels by using a pair of teflon-coated stainless steel wire electrodes with 1mm exposed tip. In order to inject lidocaine and make a lesion, insulated long dental needle with noninsulated tips were placed stareotoxically in VN and mRTN. Lidocaine of
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