A Case of Intracranial Tuberculoma and Optic Disc Tuberculoma Suspected by Miliary Tuberculosis

속립성 결핵에서 발생된 것으로 사료된 두개내 및 시신경 유두부의 결핵성 육이종 1예

  • Lim, Byung-Hun (Department of Internal Medicine, Kangbuk Samsung Hospital) ;
  • Jeon, Kyeong-Hong (Department of Internal Medicine, Kangbuk Samsung Hospital) ;
  • Cho, Yong-Kyun (Department of Internal Medicine, Kangbuk Samsung Hospital) ;
  • Hang, Ki-Eun (Department of Internal Medicine, Kangbuk Samsung Hospital) ;
  • Kim, Ki-Tack (Department of Internal Medicine, Kangbuk Samsung Hospital) ;
  • Lim, Si-Young (Department of Internal Medicine, Kangbuk Samsung Hospital) ;
  • Kim, Byeung-Ik (Department of Internal Medicine, Kangbuk Samsung Hospital) ;
  • Lee, Sang-Jong (Department of Internal Medicine, Kangbuk Samsung Hospital) ;
  • Lee, Byeung-Ro (Department of Opthalmology, Kangbuk Samsung Hospital)
  • Published : 1996.04.30

Abstract

Intracranial tuberculoma results from hematogenous spread of pulmonary, intestinal or urogenital tuberculosis. However, it might be caused by pulmonary tuberculosis, mainly. Clinically, symptoms of intracranial tuberculoma are headache and seizure, its symptoms are simillar to intracranial tumor. A 25-year-old-unmarried shopgirl was visited to this hospital because of headache, dizziness and visual disturbance for couple weeks in Sep. 1995. She had been treated with anti-tuberculosis agents of miliary tuberculosis during past nine months period. Brain MRI revealed intracranial tuberculoma and brain edema but not involved optic nerve. Ophthalmic examination revealed severe papilledema and splinter hemorrhage with bitemporal hemianopsis and central scotoma. This finding was strongly suggested of optic disc tuberculoma. Her symptoms became much better following repeated retrobulbar steroid injection with continuous anti-tuberculosis agents. We report a interesting case with intracranial tuberculoma and optic disc tuberculoma associated by miliary tuberculosis during anti-tuberculous treatment.

두개내 결핵성 육아종은 흉부, 복부 또는 요로 생식계에 있는 원발성 결핵으로 부터 결핵균이 혈행성으로 전파되어 생긴다고 하였으며, 주로 폐를 통해 침입하여 발생한다. 임상적으로 두통과 경련등의 증상을 보여 뇌종양의 양장으로 나타난다. 저자들은 속립성 결핵의 치료도중에 발생한 두통 및 현훈과 시력장애을 주소로 내원한 25세 여자환자의 뇌 자기공명영상으로 진단한 두개내 결핵성 육아종과 함께 안과 소견상 망막의 화염상출혈과 유두부종 및 시야검사상 양측두부의 반맹증과 중심암점으로 시신경의 결핵성 육아종을 의심하여 안구내의 steroid의 투약과 함께 항 결핵제제의 계속적인 투약으로 증상호전을 보인 증례을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords