Restorative Dentistry and Endodontics
- Volume 21 Issue 1
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- Pages.375-384
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- 1996
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- 2234-7658(pISSN)
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- 2234-7666(eISSN)
ROLE OF SYMPATHETIC NERVE ON THE CONTROL OF MICROCIRCULATION IN THE FELINE DENTAL PULP
고양이 치수에서 교감신경에 의한 미세순환조절에 관한 기능적 연구
- Kim, Sung-Kyo (Department of Conservative Dentistry, School of Dentistry, Kyungpook National University)
- 김성교 (경북대학교 치과대학 보존학교실)
- Published : 1996.03.20
Abstract
The purpose of this study was to investigate the functional involvement of sympathetic nerve in the control of the microcirculation in the dental pulp with the aim of elucidation of the involvement of neuropeptides and sympathetic nerve in neurogenic inflammation. Experiments were done on the 7 cats anesthetised with sodium pentobarbital, and sympathetic nerve to the' dental pulp was stimulated electrically (10 Hz, 4 V, 1.5 ms, 3.5 mins). Ana-adrenoceptor antagonist phentolamine and a neuropeptide Y antagonist D-myo-inositol-1,2,6-trisphosphate (PP56) were injected close intra-arterially into the dental pulp without changing the systemic blood pressure. The probe of laser Doppler flowmeter was placed on the buccal surface of ipsilateral canine teeth to the stimulation, and pulpal blood flow was measured. Stimulation of the sympathetic nerve decreased pulpal blood flow by
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