대한수의학회지 (Korean Journal of Veterinary Research)
- 제36권3호
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- Pages.615-619
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- 1996
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
돼지에서 감염의 조기진단 지표로서의 Haptoglobin 적용에 관한 연구
Haptoglobin as an early indicator of infection in pigs
- 문진산 (농촌진흥청 수의과학연구소) ;
- 남향미 (농촌진흥청 수의과학연구소) ;
- 구복경 (농촌진흥청 수의과학연구소) ;
- 주이석 (농촌진흥청 수의과학연구소) ;
- 정석찬 (농촌진흥청 수의과학연구소) ;
- 김종염 (농촌진흥청 수의과학연구소) ;
- 박용호 (서울대학교 수의과대학)
- Moon, Jin-san (National Veterinary Research Institute, RDA) ;
- Nam, Hyang-mi (National Veterinary Research Institute, RDA) ;
- Ku, Bok-gyeong (National Veterinary Research Institute, RDA) ;
- Joo, Yi-seok (National Veterinary Research Institute, RDA) ;
- Jung, Suk-chan (National Veterinary Research Institute, RDA) ;
- Kim, Jong-yeom (National Veterinary Research Institute, RDA) ;
- Park, Yong-ho (College of Veterinary Medicine, Seoul National University)
- 투고 : 1996.01.29
- 발행 : 1996.09.25
초록
Sera of pigs with clinically normal and infectious conditions were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis(SDS-PAGE) to demonstrate the specific changes in protein profile. In the sera from pigs with infection, haptoglobin with a 40KDa protein was found to be increased as compared to that of sera from normal pigs. As a rapid detection method for monitoring infections at large-scale farms, one of acute phase protein, haptoglobin, was selected to compare the concentrations between infectious and non-infectious conditions. Haptoglobin concentrations were low in pigs with clinically normal conditions but significantly increased in pigs with Aujesky's disease, hog cholera and parvo-virus infection. The studies provide that haptoglobin can be used as an indicator to monitor infections early at farm level.