대한수의학회지 (Korean Journal of Veterinary Research)
- 제36권3호
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- Pages.599-605
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- 1996
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
소 음경후인근의 Nitric oxide(NO) 매개성 이완
Nitric oxide(NO)-mediated relaxation of bovine retractor penis muscle
- Yang, Il-suk (Department of Veterinary Physiology, College of Veterinary Medicine, Seoul National University) ;
- Chang, Hee-jung (Chorok Animal Clinic) ;
- Kang, Tong-mook (Samsung Biomedical Research Institute) ;
- Lee, Jang-hern (Department of Veterinary Physiology, College of Veterinary Medicine, Seoul National University)
- 투고 : 1996.06.03
- 발행 : 1996.09.25
초록
This study was designed to examine the mechanism of penile erection in adult bull by analyzing the responses of bovine proximal retractor penile muscle strips(BRP) to electtical field stimulation(EFS), exogenous nitric oxide(NO), NO synthesis precursor(L-arginine), NO synthase inhibitors(L-NAME, L-NMMA), guanylate cyclase inhibitor(methylene blue) and nonspecific potassium channel blocker(tetraethylammonium, TEA) treatments. Isometric tension of BRP was measured using physiograph. Results were summarized as follows: 1. EFS of nonadrenergic noncholinrgic(NANC) nerve in BRP produced frequency-dependent inhibitory responses to the contraction induced by co-treatment of epinephrine, guanethidine and atropine. The inhibitory responses to EFS were blocked by tetrodotoxin(TTX,
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