Korean Journal of Fisheries and Aquatic Sciences (한국수산과학회지)

The Korean Society of Fisheries and Aquatic Science (한국수산과학회)
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Serum Levels of Insulin-Like Growth Factor-I in Flounder, Parlichthys olivaceus

넙치 (Parlichthys olivaceus) 혈액중 Insulin-like growth factor-I의 함유수준

  • NAM Taek-Jeong (Department of Food and Life Science, National Fisheries University of Pusan) ;
  • PARK Kie-Young (Department of Fisheries Resources Development, Kangnung National University) ;
  • LEE Young-Don (Marine Research Institute, Cheju National University) ;
  • KIM Yong-Uk (Department of Marine Biology, National Fisheries University of Pusan)
  • 남택정 (부산수산대학교 식품생명과학과) ;
  • 박기영 (강릉대학교 수산자원개발학과) ;
  • 이영돈 (제주대학교 해양연구소) ;
  • 김용억 (부산수산대학교 해양생물학과)
  • Published : 1996.03.01
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Abstract

Insulin-like growth factor-1 (IGF-I) is a mitogenic peptide with molecular mass of 7kDa. It is produced mainly in the liver and has important functions in the regulation of development and somatic growth. Recently, several investigations were undertaken to examine the biological actions and structures of IGF-I in fish. In this study, the serum levels of IGF-I were estimated from flounder, Parlichthys oilvaceus, before, during and after fasting, and the levels were accounted for 47 ng/ml, 40 ng/ml and 45 ng/ml, respectively. These results suggest that food deprivation primarily reduces IGF-I level in the blood.

양식 넙치, Paralichthys olivaceus를 실험어로 하여 동물 성장인자중의 하나인 insulin-like growth factor-I (IGF-I)의 함량을 검토하였다. 넙치의 혈액중에 존재하는 IGF-I의 양은 47ng/m1이고, 절식을 할 경우 식이를 섭취한 것에 비해 약 $15\%$ 감소하였으며, 운동에 의해서는 약 $13\%$의 감소를 보였다. 혈액중 IGF-I의 농도는 어체의 크기에 따라서도 영향이 있음을 알수 있었다.

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