Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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Volume Change of Membrane Mixed with Various Anesthetics in Halobacterium Halobium with Photo-Cyclic Energy

광순환 에너지를 갖는 Halobacterium Halobium에서 마취제의 혼합에 따른 Membrane의 부피 변화

  • Kim, Ki-Jun (Dept. of Chemical Engineering, Dae-Jin University) ;
  • Sung, Ki-Chun (Dept. of Chemical Engineering, Dae-Jin University) ;
  • Lee, Hoo-Seol (Dept. of Chemical Engineering, Dae-Jin University)
  • 김기준 (대진대학교 공과대학 화학공학과) ;
  • 성기천 (대진대학교 공과대학 화학공학과) ;
  • 이후설 (대진대학교 공과대학 화학공학과)
  • Published : 1996.11.30
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Abstract

The excess volumes of mixing of benzyl alcohol, ethyl alcohol, halothane, and procaine in vesicle and suspensions of several lipids have been determined at $25^{\circ}C$ using a excess volume dilatometer. The potency of general anesthetics has long been known to be correlated with lipid solubility. Denaturations of the bacteriorhodopsin, which is a sole membrane protein in the purple membrane of Halobacteriun Halobium, were studied by UV/Vis absorption changes. The excess volumes of mixing of benzyl alcohol and procaine in egg lecithin were all found to be negative and this result was confirmed as Miller's supposition.

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