SQUAMOUS CELL CARCINOMA OF THE SOFT PALATE AND UVULA

연구개 및 구개수에 발생한 편평세포암종

  • Kim, Chang-Lyong (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Cho, Kyu-Seung (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Kim, Ki-Young (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Lee, Seong-Hun (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Lee, Seung-Ho (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Park, Mun-Seong (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Ryu, Sun-Youl (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University)
  • 김창룡 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 조규승 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 김기영 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 이성훈 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 이승호 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 박문성 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 류선열 (전남대학교 치과대학 구강악안면외과학교실)
  • Published : 1996.12.31

Abstract

Carcinoma of the mouth accounts for approximately 5% of all carcinomas occurring in man. Carcinoma of the oral cavity develops as a result of invasion of malignant epithelial cells through the normally intact basal cell layer into subcutaneous and submucosal tissuse. The soft palate and uvula may be involved in oral cancer but are not common sites. Early lesions of soft palate carcinoma appear as red, white, or mixed changes in the mucosa. The earliest symptom is mild sore throat. Advanced lesions interfer with swallowing and may cause a voice change. Although surgical method of soft palate carcinoma is successful, prognosis is relatively poor due to swallowing and speech problem. Occasionally marginal recurrence may be developed. This article reports a case of squamous cell carcinoma occurred unusually in the soft palate and uvula. The case was treated with neoadjuvant chemotherapy, local radical excision and postoperative irradiation. Patient was followed up for 2 years. There was no tumor recurrence. The overall result including function was satisfactory.

독특한 해부학적 구조와 상기도에서 수행하는 기능으로 인해 수술후에 발음이나 연하에 심각한 문제를 야기할 수 있는 연구개 및 구개수에 발생한 편평세포암종 환자에서, 저자들은 술전 항암화학요법과 외과적 절제술 그리고 6000 cGy의 방사선 조사를 시행하여 치료하였다. 2년 이상 경과한 현재까지 재발의 소견은 관찰되지 않고 비교적 양호한 기능을 보이고 있다.

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