USE OF DEMINERALIZED AND MINERALIZED FREEZE-DRIED ALLOGENIC BONE GRAFT FOR THE CORRECTION OF MAXILLOFACIAL DEFORMITIES; CASE REPORTS

악골결손 재건을 위한 탈회 및 비탈회 동결건조 동종골의 이용

  • E, Gi-Hyug (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Chosun University.) ;
  • Yeo, Hwan-Ho (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Chosun University.) ;
  • Kim, Young-Kyun (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Chosun University.) ;
  • Kim, Su-Gwan (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Chosun University.) ;
  • Lee, Byung-Joon (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Chosun University.) ;
  • Park, In-Soon (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Chosun University.) ;
  • Um, In-Woong (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Wonkwang University)
  • 이기혁 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 여환호 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 김영균 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 김수관 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 이병준 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 박인순 (조선대학교 치과대학 구강악안면외과학교실) ;
  • 엄인웅 (원광대학교 치과대학 구강악안면외과학교실)
  • Published : 1996.09.30

Abstract

Bone graft has been used to repair one defect caused by disease and trauma, congenital and acquired deformities. Graft materials are autogenous bone, allogenic bone, xenogenic bone, synthetics. Autogenous bone graft is the most superior to other materials for immunologic reaction, compatibility to host tissue, and revascularization. However, autogenous bone graft is required for additional operation and the amount of taking is limited. Autografts are obtained at own expense and also limited in size, shape. In order to compensate these problems, allogenic bone graft has been used increasingly. But allogenic bone graft encounters immunologic complications. Therefore, it has been used after freezing, lyophilization, or demineralization. Allogenic bone processed by only lyophilization includes potential antigenic properties on its surface, therefore it is demineralized to deplete immunologic reaction. Demineralized bone releases BMP and helps the mesenchymal cells transform to the chondroblast to produce cartilage and bone. This reaction is called osteoinducation. Many authors have reported that mineralized lyophilized bone had less antigenicity clinically and favorable bony consideration with host bone. In our department from 1995 to now, we have used banked allogenic bone graft that has been prepared from Wonkwang Bone Bank in 5 cases and mineralized lyophilized bone graft in 2 cases to reconstruct the maxillofacial bone defect after tumor resection and cyst enucleation and cleft alveolus. We will report with literature review that the result is favorable functionally and esthetically.

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