Maxillofacial Plastic and Reconstructive Surgery
- 제18권2호
- /
- Pages.261-268
- /
- 1996
- /
- 2288-8101(pISSN)
- /
- 2288-8586(eISSN)
가토 하치조신경 재생에 있어 Nerve Growth Factor의 효과
EFFECT OF NERVE GROWTH FACTOR IN REGENERATION OF MANDIBULAR NERVE OF RABBIT
- Park, Kwang (Department of Oral & Maxillofacial Surgery, Kangju Veterans Hospital) ;
- Kim, Hyun-Tae (Department of Oral & Maxillofacial Surgery, Uijongbu St. Mary's Hospital, Catholic University Medical College) ;
- Lee, Jong-Ho (Department of Oral & Maxillofacial Surgery, Seoul National University)
- 발행 : 1996.06.30
초록
An experimental study was performed to evaluate the efficacy of nerve growth factor(NGF) on inferior alveolar nerve in a rabbit model. In 20 New Zealand white rabbits, 14mm of bilat eral alveolar nerve were resected and the defects were repaired with the 17mm silicone conduits. In group I, 5mm autologous nerve segment were located centrally in the left side after tubulization and NGF solution(Sigma chemical 0.1 mg/mL) was instilled into each conduit. In group II, nerve repair modality was the same but no NGF solution was instilled into the conduits. On 2 months and 6 months postoperatively, the results were evaluated by clinical and hist omorphometric assessment. The result was that autologous nerve segment group show the best nerve regeneration effect and NGF instilled group the worst.
키워드