A study on Chemical Constituents from Marine Sponge Luffariella sp.

해양 해면 Luffariella sp.의 화학적 성분에 대한 연구

  • Park, Sun Ku (Youngsan River Water Resource Research Institute National Institute of Environmental Research) ;
  • Kim, Taek Jae (Youngsan River Water Resource Research Institute National Institute of Environmental Research) ;
  • Cho, Hyun-Woo (Department of Chemistry, Kyonggi University)
  • 박선구 (국립환경연구원 영산강수질검사소) ;
  • 김택제 (국립환경연구원 영산강수질검사소) ;
  • 조현우 (경기대학교 이과대학 화학과)
  • Received : 1996.08.14
  • Published : 1996.12.25

Abstract

The two metabolites, Aaptamine(1) and Demethyl(oxy)aaptamine(2) were isolated from marine Sponge Luffariella sp., collected in October 1992, Manado Bay, Sulawesi in Indonesia showed in vitro activity against KB cancer cell line. Their structures were elucidated by $^1H-$, $^{13}C-NMR$, $^1H-^{13}C$(1 bond) heteronuclear multiple quantum coherence spectroscopy(HMQC), electron ionization mass spectroscopy(EIMS), ultra-violet spectroscopy(UV) and infrared spectroscopy(IR).

인도네시아 Manado만의 Sulawesi에서 채집한 KB cancer cell line에 대해 in vitro로 활성을 가지고 있는 것으로 추정되는 해면 Luffariella sp.로부터 Aaptamine(1) 및 Demethyl(oxy)aaptamine(2)을 분리하였다. 이들 화합물의 화학구조는 $^1H-$, $^{13}C-NMR$, $^1H-^{13}C$(1 bond) heteronuclear multiple quantum coherence spectroscopy(HMQC), electron ionization mass spectroscopy(EIMS), UV 및 IR에 의해 밝혔다.

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