Journal of Korean Academy of Oral and Maxillofacial Radiology (치과방사선)

Korean Academy of Oral and Maxillofacial Radiology (대한영상치의학회)
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ELECTRON MICROSCOPIC STUDY OF THE IRRADIATION EFFECT ON THE RAT MANDIBULAR CONDYLE

방사선조사가 하악과두에 미치는 영향에 관한 전자현미경적 연구

  • Park Myoung Seon (Department of Oral and Maxillofacial Radiology, Graduate School, Seoul National University) ;
  • Park Tae Won (Department of Oral and Maxillofacial Radiology, Graduate School, Seoul National University)
  • 박명선 (서울대학교 치과대학 구강악안면방사선학 교실) ;
  • 박태원 (서울대학교 치과대학 구강악안면방사선학 교실)
  • Published : 1996.08.01
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Abstract

In attempt to determine radiation effect on the mandibular condyle of the growing rat, 27 white female rats (Sprague-Dawley) were divided into 3 groups and irradiated respectively 5Gy, 10Gy, 20Gy using MK Cell Irradiator. Mandibular condyles from rats on the day of 1, 7, 14 after the irradiation day were obtained, sectioned sagittally and examined by light microscopy, and thereafter middle portion through anteroposterior direction on the sagittal plane was selected to examine the ultrastructural change by transmission electron microscopy. The obtained results are followings. 1. In the proliferative zone some cells showed little organelles in case of 5Gy irradiation, in addition the number of degenerative cells increased and in case of 10Gy irradiation, and in case of 20 Gy irradiation total number of cells decreased. 2. In the hypertrophic zone, narrowing of width and partial disorder in hypertrophic process were noted in case of 5 Gy irradiation, and more prominent narrowing of width and more irregular disorder in hypertrophic process in case of both 10Gy and 20Gy irradiation. 3. In the upper hypertrophic zone some chondrocytes seemed to be dying and the polarity of nuclei could not be seen, if any. 4. The periodic observation showed the severest change at day 7 and the signs of recovery at day 14 after irradiation.

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