YAKHAK HOEJI (약학회지)
- Volume 40 Issue 3
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- Pages.300-305
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- 1996
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Ring Opening of Pyrolidine and Formation of N-Protected Amino Ketones; Synthesis of 5-Amino-2-pentanone Derivatives
피롤리딘의 개환과 N-프로텍티드 아미노 케톤의 형성; 5-아미노-2-펜타논 유도체의 합성
- Park, Myung-Sook (College of Pharmacy, Duksung Women's University)
- 박명숙 (덕성여자대학교 약학대학)
- Published : 1996.06.01
Abstract
The base-induced elimination of N-protected 2-(bromomethyl)pyrrolidines 12a-c with KHMDS in THF at -78
Keywords
- Base-induced elimination of alkyl halides;
- Formation of enamines;
- Hydrolysis of n-iminium intermediates;
- Synthesis of amino ketones (5-amino-2-pentanones)