Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
권호 표지

An Antifungal Compound Against Phytophthora capsici Produced by Streptomyces sp. 3D3

Streptomyces sp. 3D3 균주가 생산하는 항고추역병성 항생물질

  • Yun, Bong-Sik (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Kim, Chang-Jin (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Lee, In-Kyoung (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Hiroyuki, Koshino (The Institute of Physical and Chemical Research (RIKEN)) ;
  • Yoo, Ick-Dong (Korea Research Institute of Bioscience and Biotechnology, KIST)
  • 윤봉식 (한국과학기술연구원 생명공학연구소) ;
  • 김창진 (한국과학기술연구원 생명공학연구소) ;
  • 이인경 (한국과학기술연구원 생명공학연구소) ;
  • 히로유끼 고시노 (이화학연구소, 일본) ;
  • 유익동 (한국과학기술연구원 생명공학연구소)
  • Published : 1996.02.01
Download PDF
⟨ Previous Next ⟩

Abstract

During the screening for the antifungal compounds against Phytophthora capsici causing phytophthora blight of red pepper, we isolated a strong active compound, bafilomycin $C_1$, produced by strain 3D3. The producing organism was identified as Streptomyces sp. based on taxonomic studies. The antifungal compound was purified from culture broth by HP-20 column chromatography, ethylacetate extraction, silica gel column chromatography and HPLC, and was identified as bafilomycin $C_1$ by color reaction, UV and $^{1}H$-NMR spectral data analysis. Bafilomycin $C_1$ showed strong antifungal activity against various phytopathogenic fungi.

Keywords