Dietary Copper Intake and Effect of Zinc Supplementation on Plasma Copper Level in Korean Adults

한국성인의 구리 섭취 및 아연 보충에 의한 혈장구리 농도 변화

  • 천종희 (인하대학교 가정대학 식품영양학과)
  • Published : 1996.06.01

Abstract

The purpose of this study was to analyse copper intake and effect ofZn(30mg ZnSO4/d) supplementation on plasma copper level of Korean adults. Daily Cu intakes were studied in ninety subjects aging 20-20 years. Among them twenty four subjects participated in 6 weeks Zn supplementation study. The men consumed 1.47($\pm$0.64)mg of Cu and the women consumed 0.98($\pm$0.43)mg of Cu daily. the most abundant sources of Cu was meat, fish, egg and soybean group, the second was cereal and grain group and the third was vegetable group. These three groups supplied about 90% of copper in the subjects. The plasma copper level of the subjects was not changed much until two weeks of Zn supplementation. However, after two weeks of Zn supplementation plasma copper level was reduced continuously during the experiment. There was no significant difference in plasma Cu level between control and supplement group of the men, while the supplemented women showed significantly lower plasma Cu level than control group at week 4(p<0.01) and week 6(p<0.05). Although plasma Cu level of the subjects was slightly changed, its concentration in plasma was still in normal range in all groups and no one showed clinical Cu deficiency. Therefore the Zn supplementation of RDA level doesn't seem to cause any adverse effect on Cu status.

Keywords

References

  1. 한국인영양권장량(제 6차 개정) 한국영양학회
  2. J Am Diet Assoc v.88 Copper nutriture, bioavailability, and the influence of dietary factors. Turnlund,J.R.
  3. Copper in Animals and Man Copper Interactions Gawthorne,J.M.;Howell(ed.)Gawthorne(ed.)
  4. Modern Nutrition in Health and Disease Copper Turnlund,J.R.;Shils ed.
  5. Atherosclerosis v.29 Cholesterolemia and cardiovascular abnormalities in rats caused by copper deficiency. Allen,K.G.D;Klevay,L.M.
  6. Atherosclerosis v.31 Copper deficiency and cholesterol metabolism in the rat. Allen,K.G.D.;Klevay,L.M.
  7. Am J Clin Nutr v.33 The effect of dietary copper and zinc on cholesterol metabolism. Peter,W;Fischer,F.
  8. 한국영양학회지 v.20 no.5 제주 지역 농촌 주부들의 영양소 섭취실태 오영주;황인주;우순자
  9. 한국영양식량학회지 v.19 no.5 일부 농촌 주부의 무기질 섭취와 혈청지질, 무기질 함량비교 이승교;이동태;김화님;김애정;승정자
  10. 숙명여자대학교 석사학위논문 일부 지역 농촌 부인의 Fe, Cu, Zn 섭취 수준 및 혈액 성상에 관한 연구 김애정
  11. 한국영양학회지 v.26 no.1 농촌 성인 남녀의 무기질 섭취량, 혈액수준 및 소변 중 배설량과 혈압과의 관계에 관한 연구 승정자;최미경;조재홍;이주연
  12. 한국영양식량학회지 v.20 no.1 한국 여자 대학생의 Iron, Copper 및 Cobalt 평형에 관한 연구 장수영;최인선;오승호
  13. 한국영양학회지 v.24 no.6 위암환자의 혈청내 구리 및 아연 농도에 관한 연구 정유덕;홍석일;나혜복;심영현
  14. 한국영양학회지 v.26 no.3 한국의 일부 가임여성과 임산부의 혈장 내 아연 및 구리 농도에 관한 연구 하은정;나혜복
  15. Composition of foods
  16. Clin Chem v.17 no.5 Simultaneous direst estimation by atomic absorption spectrophotometry of Cu and Zn in serum, urine and cerebrospinal fluid. Matet.S;Henkin,R.I.
  17. Trace Elements in Human and Animal Nutrition Copper Davis,G.K.;Mertz,W.;Mertz(ed.)
  18. Am J Clin Nutr v.41 Effect of Zn intake on Cu excretion and retention in men Festa,M.D.;Anderson,H.L.;Dowdy,R.P.;Ellersieck,M.R.
  19. Copper and Environment Interactions of Copper with Other Trace Elements Kichgessner,M.;Nriugu(ed.)
  20. 한국영양학회지 v.26 no.9 한국 성인의 아연섭취실태 및 아연보충에 의한 아연영양상태 변화 박진숙;천종희