The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Studies on immunomodulating Function of Components Separated from Platycodi Radix

길경의 면역조절 기능성에 관한 연구

  • Bae, Man-Jong (Dept. of Food Sciencd, Kyungsan University) ;
  • Park, Mu-Hui (Dept. of Food Science and Technology, Yeungnam University) ;
  • Son, Gyu-Mok (Dept. of Food and Nutrution, Changwon College)
  • 배만종 (경산대학교 식품과학과) ;
  • 박무희 (영남대학교 식품가공학과, 창원전문대학 식품영양학과) ;
  • 손규목
  • Published : 1996.03.01
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Abstract

In order to research for compound of immunomodulatic and anti-allergic function. These experiments were conducted to investigated the effects of hot water extracts(PRWE) , ethanol extracts (PREE) and polysaccharide fraction extracts (PRPE) extracted from platycodi radix on immune response. The effect of these platycodi radix extracts on hemagglutinin titer(HA), hemalysin titer(HY), plaque forming cell(PFC), rosette forming cell (RFC) and phagocytosis was Investigated by using BALB / C mice. The results obtained from this study are as follows. Generally, the oral administration of extracts fractions for 10 days each other resulted in the enhanced HA and HY. In the experiment of PFC and RFC, the results of experimental groups which was given each samples compared to control group showed the enhanced level of activity such as PRPE 160% and 196% each other But PRWE and PREE decreased or wear not changed. When PREE, PRPE or PRWE was given to mice orally, PREE and PRPE significantly enhanced the phagocytic activity of peritoneal exudate cells(PEC), spleen cells(SC) and monolymphocytus cell(MC), about from 150% to 250%, but PRW was decreased.

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