Preventive Nutrition and Food Science

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
권호 표지

Bacteriocins: Assay, Biochemistry, and Mode of Action

  • Paik, Hyun-Dong (Dept. of Food Engineering, Kyungnam University, Masan 631-701)
  • Published : 1996.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

Bacteriocins are proteins produced by a heterogeneous group of bacteria that have a bactericidal effect on closely related organisms. Recently, bacteriocins from lactic acid bacteria and other food-related organisms have been the subject of much research because of their potential as food biopreservatives. Various modifications of agar plate diffusion assays are the most widely used methods even though the limitations of such assays are generally recognized. The ability to obtain a concentrated crude preparation on bacteriocin by optimizing production parameters greatly simplifies recovery of bacteriocin on subsequent purification steps. Some studies performed to optimize bacteriocins have been purified to homogeneity, and the amino acid sequences of many of these purified bacteriocins have been determined. Obtaining characterization data on purified bacteriocin will minimize the risk of overlapping of research and confusion on identification of these compounds. Several me-chanisms leading to cell death have been hypothesized. These include depletion of the proton motive force(PMF) across the cell membrane: RNase and/or DNase activity within the sensitive cell; and pore formation and lysis of sensitive cells at the cell membrane.

Keywords

References

  1. Food biopreservatives of microbial origin Cells of lactic acid bacteria as food biopreservatives Ray,B.;Ray,B.(ed.);Daeschel.M.(ed.)
  2. Bacteriol. Rev. v.40 Bacteriocins of gram-positive bacteria Tagg,J.R.;Dajani,A.S.;Wannamaker,L.W.
  3. Bacteriocins of lactic acid bacteria Biochemical methods for purification of bacteriocins Muriana,P.M.;Luchansky,J.B.;Hoover,D.G.(ed.);Steenson,L.R.(ed.)
  4. Appl. Microbiol. v.21 Assay system for bacteriocins Tagg,J.R.;McGiven,A.R.
  5. Antibiotics : Assessment of antimicrobial activity and resistance Theory of antibiotic inhibition zone formation, disc sensitivity methods and MIC determinations Linton,A.H.;Denver,A.D.(ed.);Quesnel.L.B.(ed.)
  6. J. Appl. Bacteriol. v.68 Techniques used for the determination of antimicrobial resistance and sensitivity in bacteria Piddock,L.J.V.
  7. J. Food Prot. v.59 Improvement of detection and production of propionicin PLG-1, a bacteriocin Produced by Propionibacterium thoenii Hsieh,H.;Paik,H.D.;Glatz,B.A.
  8. Bacteriocins of lactic acid bacteria Screening methods for detecting bacteriocin activity Hoover,D.G.;Harlander,S.K.;Hoover,D.G.(ed.);Steenson,L.R.(ed.)
  9. Methods in microbiology v.7A Methods for studying bacteriocins Mayr-Harting,A.;Hedges,A.J.;Berkeley,R.C.W.;Bergen,T.(ed.);Norris,J.R.(ed.)
  10. Int. J. Food Sci. Technol. v.25 An enzyme immunoassay for nisin Falahee,M.B.;Adams,M.R.;Dale,J.W.;Morris,B.A.
  11. J. Microbiol. Methods. v.14 A quantitative method for assessing bacteriocins and other food antimicrobials by automated turbidometry Skytta,E.;Mattila-Sandholm,T.
  12. Lett. Appl. Microbiol. v.13 Assay system for detecting bacteriocin in microdilution wells Toba,T.;Samant,S.K.;Itoh,T.
  13. Lett. Appl. Microbiol. v.14 Detection of bacteriocin activity in bacteria using hydrophobic grid membrane filters Ryser,E.T.;Richard,J.A.
  14. Lett. Appl. Microbiol. v.17 Methods to demonstrate the bactericidal activity of bacteriocins Benkerroum,N.;Ghouati,Y.;Sandine,W.E.;Tantaoui-Elaraki,A.
  15. Food Microbiol. v.11 Factors influencing production of bacteriocins by lactic acid bacteria Yang,R.;Ray,B.
  16. Appl. Microbiol. v.24 Effect of the medium on bacteriocin production among strains of Streptococcus mutans Rogers,A.H.
  17. Indian J. Daity Sci. v.27 Effect of different inorganic and organic salts on nisin production in a broth culture Kalra,M.S.;Dudani,A.T.
  18. J. Gen. Microbiol. v.138 Influence of the carbon source on nisin production in Lactococcus lactis subsp. lactis batch fermentations Vuyst.L.D.;Vandamme,E.J.
  19. Appl. Microbiol. Biotechnol. v.40 Influence of the phosphorous and nitrogen source on nisin production in Lactococcus lactis subsp. lactis batch fermentations using a complex medium Vuyst,L.D.;Vandamme,E.J.
  20. J. Food Sci. v.58 Pediococus acidilactici PO2 bacteriocin production in whey permeate and inhibition of Listeria monocytogenes in foods Liao,C.;Yousef,A.E.;Richter,E.R.;Chism.G.W.
  21. J. Appl. Bacteriol. v.73 A comparison of factors affecting the production of two bacteriocins from lactic acid bacteria Parente,E.;Hill,C.
  22. J. Appl. Bacteriol. v.75 The influence of pH and growth rate on production of the bacteriocin, bavaricin MN, in batch and continuous fermentations Kaiser,A.L.;Montville,T.J.
  23. Appl. Environ. Microbiol. v.57 Influence of growth conditions in the production of a bacteriocin, pediocin AcH, by Pediococcus acidilactici H. Biswas,S.R.;Ray,P.;Johnson,M.C.;Ray,B.
  24. J. Bacteriol. v.174 A novel lactococcal bacteriocin whose activity depends on the complementary action of two peptides Nissen-Meyer,J.;Holo,H.;Havarsteinl,L.S.;Sletten,K.;Nes,I.F.
  25. unpublished data Barefoot,S.F.
  26. Appl. Environ. Microbiol. v.60 Purification and partial amino acid sequence of curvaticin FS47, a heat-stable bacteriocin produced by Lactobacillus curvatus FS47 Garver,K.I.;Muriana,P.M.
  27. Appl. Environ. Microbiol. v.37 Bacteriocin production by Clostridium acetobutylicum in an industrial fermentation process Barber,J.M.;Robb,F.T.;Webster,J.R.;Woods,D.R.
  28. Appl. Microbiol. Biotechnol. v.41 Influence of pH on growth and bacteriocin production by Lactococcus lactis subsp. lactis 140NWC during batch fermentation Parente,E.;Ricciardi,A.;Addario,G.
  29. Int. J. Food Microbiol. v.20 Bacteriocin production by Carnobacterium piscicola LV 61 Schillinger,U.;Stil,M.E.;Holzapfel,W.H.
  30. Appl. Microbiol. Biotechnol. v.39 Influence of growth conditions on production and activity of mesentericin 5 by a strain of Leuconostoc mesenteroides Daba,H.;Lacroix,C.;Huang,J.;Simard,R.E.
  31. Appl. Environ. Microbiol. v.58 Production of an amylase sensitive bacteriocin by an atypical Leuconostoc paramesenteroides strain Lewus,C.B.;Sun,S.;Montville,T.J.
  32. Antimicrob. Agents. Chemother. v.26 Purification and characterization of the Lactobacillus acidophilus bacteriocin lactacin B. Barefoot,S.F.;Klaenhammer,T.R.
  33. Biosci. Biotech. Biochem. v.56 Plasmid-associated bacteriocin production by and immunity of Lactobacillus acidophilus TK8912 Kanatani,K.;Tahara,T.;Yoshida,K.;Miura,H.;Sakamoto,M.;Oshimura,M.
  34. Nisin. Adv. Appl. Microbiol. v.27 Hurst,A.
  35. J. Bacteriol. v.167 Characteriation and purification of helveticin J and evidence for a chromosomally determined bacteriocin produced by Lactobacillus helveticus 481 Joerger,M.C.;Klaenhammer,T.R.
  36. J. Gen. Microbiol. v.136 Plasmid-associated bacteriocin production by a Lactobacillus sake strain Mortvedt,C.I.;Nes,I.F.
  37. Appl. Environ. Microbiol. v.57 Partial purification and characterization of a bacteriocin produced by Propioni-bacterium thoenii Lyon,W.J.;Glatz,B.A.
  38. J. Appl. Bacteriol. v.74 Purification, partial characterization and plasmid-linkage of pediocin SJ-1, a bacteriocin produced by Pediococcus acidilactici Schved,F.;Lalazar,A.;Henis,Y.;Juven,B.J.
  39. J. Appl. Bacteriol. v.77 Lactoferricin, a new antimicrobial peptide Jones,E.M.;Smart,A.;Bloomberg,G.;Burgess,L.;Millar,M.R.
  40. Biochimie v.70 Bacteriocins of lactic acid bacteria Klaenhammer,T.R.
  41. Appl. Environ. Microbiol. v.53 Plasmid-associated bacteriocin production and sucrose fermentation in Pediococcus acidilactici Gonzalez,C.F.;Kunka,B.S.
  42. Appl. Environ. Microbiol. v.56 Plasmid-associated bacteriocin production by a strain of Carnobacterium piscicola from meat Ahn,C.;Stiles,M.E.
  43. J. Gen. Microbiol. v.137 Plasmid-encoded determinants for bacteriocin production and immunity in a Lactococcus lactis strain and purification of the inhibitory peptide Dufour,A.;Thuault,D.;Boulliou,A.;Bourgeois,C.M.;Pennec,J.L.
  44. Appl. Environ. Microbiol. v.62 An application in cheddar cheese manufacture for a strain of Lactococcus lactis producing a novel broad-spectrum bacteriocin, lacticin 3147 Ryan,M.P.;Rea,M.C.;Hill,C.;Ross,R.P.
  45. Appl. Environ. Microbiol. v.58 Jenseniin G, a heat-stable bacteriocin produced by Propionibacterium jensenii P126 Grinstead,D.A.;Barefoot,S.F.
  46. J. Microbiol. Biotechnol. v.6 Purification, characterization and comparison of bacteriocins Paik,H.D.;Oh,D.W.
  47. J. Gen. Microbiol. v.138 Purification and amino acid sequence of a bacteriocin produced by Pediococcus acidiactici LozanoJ.C.N.;Nissen-Meyer,J.;Sletten,K.;Pelaz,C.;Nes,I.F.
  48. System. Appl. Microbiol. v.15 Characterization of the bacteriocins curvacin A from Lactobacillus curvaticus LTH1174 and sakacin P from L. sake LTH673 Tichaczek,P.S.;Nissen-Meyer,J.;Nes,I.F.;Vogel,R.F.;Hammes,W.P.
  49. J. Gen. Microbiol. v.138 Purification and amino acid sequence of sakacin A. a bacteriocin from Lactobacillus sake Lb706 Holck,A.L.;Axelsson,L.;Birkeland,S.E.;Aukrust,T.;Blom,T.
  50. J. Gen. Microbiol. v.139 Purification and characterization of plantaricin A. a Lactobacillus plantarum bacteriocin whose activity depends on the action of two peptides Nissen-Meyer,J.;Larsen,A.G.;Sletten,K.;Daeschel,M.;Nes,I.F.
  51. J. Appl. Bacteriol. v.75 Antimicrobial activity of lactic acid bacteria isolated from sour doughs : Purification and characterization of bavaricin A, a bacteriocin produced by Lactobacillus bavaricus M1401 Larsen,A.G.;Vogensen,F.K.;Josephsen,J.
  52. Curr. Microbiol. v.29 Purification and cloning of piscicolin 61, a bacteriocin from Carnobacterium piscicola LV61 Holck,A.L.;Axelsson,L.;Schillinger,U.
  53. Appl. Environ. Microbiol. v.61 Purification and partial amino acid sequence of plantaricin S, a bacteriocin produced by Lactobacillus plantarum LPCO 10, the activity of which depends on the complementary action of two peptides Jimenea-Diaz,R.;Ruiz-Barba,J.L.;Cathcart,D.P.;Holo,H.;Nes,I.F.;Sletten,K.H.;Warner,P.J.
  54. Appl. Environ. Microbiol. v.62 Isolation, partial characterization, and mode of action of acidocin J1132, a two-component bacteriocin produced by Lactobacillus acidophilus JCM 1132 Tahara,T.;Oshimura,M.;Umezawa,C.;Kanatani,K.
  55. Appl. Environ. Microbiol. v.62 Biochemical and genetic characterization of enterocin A from Enterococcus faecium, a new antilisterial bacteriocin in the pediocin family of bacteriocins Aymerich,T.;Holo,H.;Havarstein,L.S.;Hugas,M.;Gerriga,M.;Nes,I.F.
  56. J. Bacteriol. v.173 Characterization of leucocin A-UAL 187 and cloning of the bacteriocin gene from Leuconostoc gelidum Hastings,J.W.;Sailer,M.;Johnson,K.;Roy,K.L.;Vederas,J.C.;Stiles,M.E.
  57. Appl. Environ. Microbiol. v.57 Purification and partial characterization of lactacin F, a bacteriocin produced by Lactobacillus acidophilus 11088 Muriana,P.M.;Klaenhammer,T.R.
  58. J. Gen. Microbiol. v.138 Characterization and purification of mesentericin Y105, an anti-Listeria bacteriocin from Leuconostocmesenteroides Hechard,Y.;Derijard,B.;Leteller,F.;Cenatiempo,Y.
  59. Appl. Environ. Microbiol. v.58 Purification and partial characterization of lacticin 481, a lanthionine-containing bacteriocin produced by Lactococcus lactis subsp. lactis CNRZ 481. Piard,J.C.;Muriana,P.M.;Desmazeaud,M.J.;Klaenhammer,T.R.
  60. Appl. Environ. Microbiol. v.59 Isolation and characterization of the lantibiotic salivaricin A and its structural gene salA from Streptococcus salivarius 20P3 Ross,K.F.;Ronson,C.W.;Tagg,J.R.
  61. Appl. Environ. Microbiol. v.60 Staphylococcin 1580 is identical to the lantibiotic epidermin : Implications for the nature of bacteriocins from gram-positive bacteria Sahl,H.
  62. Lait v.75 Purification and partial amino acid sequence of propionicin PLG-1, a bacteriocin produced by Propionibacterium thoenii P127 Paik,H.D.;Glatz,B.A.
  63. Appl. Environ. Microbiol. v.62 Characterization of the chemical and antimicrobial properties of piscicolin 126, a bacteriocin produced by Carnobacterium piscicola JG126 Jack,R.W.;Wan,J.;Gordon,J.;Harmark,K.;Davidson,B.E.;Hillier,A.J.;Wettenhall,R.E.H.;Hickey,M.W.;Coventry,M.J.
  64. Guide to protein purification High-performance liquid chromatography: Effective protem purification by various chromatographic modes Chicz,R.M.;Regnier,F.E.;Deutscher,M.P.(ed.)
  65. Guide to protein purification Limited N-terminal sequence analysis Matsudaira,P.;Deutscher,M.P.(ed.)
  66. Bacteriocin of lactic acid bacteria Antimicrobial proteins : Clasification, nomenclature, diversity, and relationship to bacteriocins Montville,T.J.;Kaiser,A.L.;Hoover,D.G.(ed.);Steenson,L.R.(ed.)
  67. Appl. Environ. Microbiol. v.59 Common mechanistic action of bacteriocins from acid bacteria Bruno,M.E.C.;Montville,T.J.
  68. Appl. Environ. Microbiol. v.57 Mechanism of action of the peptide antibiotic nisin in liposomes and cytochrome C oxidase-containing proteoliposomes Gao,F.H.;Abee,T.;Konings,W.N.
  69. Appl. Environ. Microbiol. v.58 Depletion of proton motive force by nisin in Listeria monocytogenes cells Bruno,M.E.C.;Kaiser,A.;Montville,T.J.
  70. J. Bacteriol. v.173 The bacteriocin lactococcin A specifically increases permeability of lactococcal cytoplasmic membranes in a voltage-independent, protein-mediated manner van Belkum,M.J.;Kok,J.;Venema,G.;Holo,H.;Nes,I.F.;Konings,W.N.;Abee,T.
  71. Appl. Environ. Microbiol. v.59 Mode of action of lactococcin B, thio-actovated bacteriocin from Lactococcus lactis Venema,K.;Abee,T.;Haandrikman,A.J.;Leenhouts,K.J.;Kok,J.;Konings,W.N.;Venema,G.
  72. Appl. Environ. Microbiol. v.58 Collapse of the proton motive force in Listeria monocytogenes caused by a bacteriocin produced by Pediococcus acidilactici Christensen,D.P.;Hutkins,R.W.
  73. Appl. Environ. Microbiol. v.59 Pediocin PA-1, a bacteriocin from Pediococcus acidilactici PAC1.0, forms hydrophilic pores in the cytoplasmic membrane of target cells Chikindas,M.L.;Garcia-Garcera,M.J.;Driessen,A.J.M.;Ledeboer,A.M.;Nissen-Meyer,J.;Nes,I.F.;Abee,T.;Konnings,W.N.;Venema,G.
  74. J. Appl. Bacteriol. v.76 Interaction of the bacteriocin pediocin SJ-1 with the cytoplasmic membrane of sensitive bacterial cells as detected by ANS fluorescence Schved,F.;Lindner,P.;Juven,B.J.
  75. J. Bacteriol. v.175 Membrane permeabilization of Listeria monocytogenes and mitochondria by the bacteriocin mesentericin Y105 Maftah,A.;Renault,D.;Vignoles,C.;Hechard,Y.;Bressolher,P.;Ratinaud,M.H.;Cenatiempo,Y.;Julien,R.
  76. FEMS Microbiol. Rev. v.12 Genetics of bacteriocin produced by lactic acid bacteria Klaenhammer,T.R.
  77. Appl. Environ. Microbiol. v.60 Kinetic studies of the action of lactacin F, a bacteriocin produced by Lactobacillus johnsonii that forms poration complexes in the cytoplasmic membrane Abee,T.;Klaenhammer,T.R.;Letellier,L.
  78. Appl. Environ. Microbiol. v.62 Bactericidal mode of action of plantaricin C. Gonzalez,B.;Glaasker,E.;Kunji,E.R.S.;Driessen,A.J.M.;Suarez,J.E.;Konings,W.N.
  79. Ph. D. dissertation, Iowa State Univ. Enhanced production, purification, and characterization of propionicin PLG-1. a bacteriocin produced by Propionibacterium thoenii P127 Paik,H.D.